Ubiquilin 1 Products
(Ubiquilin 1 (UBQLN1))
Categories
This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured Ubiquilin 1 Categories
Ubiquilin 1 Antibodies
High quality antibodies with extensive validation data.
Ubiquilin 1 ELISA Kits
Reliable ELISA kits for a wide range of species.
Ubiquilin 1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Ubiquilin 1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p), IF
Validations
- (3)
- (3)
Cat. No.
ABIN388966
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Monkey, Rabbit, Sheep
Application
WB, IHC, IHC (p)
Validations
- (4)
Cat. No.
ABIN6741620
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF
Validations
- (5)
Cat. No.
ABIN3029415
Quantity
0.4 mL
Datasheet
Datasheet
Recommended Ubiquilin 1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6971031
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6208313
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1164827
Quantity
96 tests
Datasheet
Datasheet
Recommended Ubiquilin 1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324458
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2734885
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2734886
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our Ubiquilin 1 products
: "APP modulates KCC2 expression and function in hippocampal GABAergic inhibition." in: eLife, Vol. 6, (2018) (PubMed).: "MiR-200c inhibits autophagy and enhances radiosensitivity in breast cancer cells by targeting UBQLN1." in: International journal of cancer. Journal international du cancer, Vol. 136, Issue 5, pp. 1003-12, (2014) (PubMed).
: "Tau pathology in frontotemporal lobar degeneration with C9ORF72 hexanucleotide repeat expansion." in: Acta neuropathologica, Vol. 125, Issue 2, pp. 289-302, (2013) (PubMed).
: "UBQLN1 interacts with SPEM1 and participates in spermiogenesis." in: Molecular and cellular endocrinology, Vol. 327, Issue 1-2, pp. 89-97, (2010) (PubMed).
: "Activation of CD47 receptors causes proliferation of human astrocytoma but not normal astrocytes via an Akt-dependent pathway." in: Glia, Vol. 59, Issue 2, pp. 308-19, (2010) (PubMed).
: "Overexpression of ubiquilin decreases ubiquitination and degradation of presenilin proteins." in: Journal of Alzheimer's disease : JAD, Vol. 6, Issue 1, pp. 79-92, (2004) (PubMed).
: "Interaction with a ubiquitin-like protein enhances the ubiquitination and degradation of hepatitis C virus RNA-dependent RNA polymerase." in: Journal of virology, Vol. 77, Issue 7, pp. 4149-59, (2003) (PubMed).
: "The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome." in: Molecular cell, Vol. 6, Issue 2, pp. 409-19, (2000) (PubMed).
: "Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulation." in: The Journal of cell biology, Vol. 151, Issue 4, pp. 847-62, (2000) (PubMed).
Synonyms and alternative names related to Ubiquilin 1
ubiquilin 1 (UBQLN1), ubiquilin 1 (Ubqln1), 1110046H03Rik, 1810030E05Rik, AU019746, C77538, D13Ertd372e, DA41, Da41, DSK2, Dsk2, PLIC-1, Plic-1, Plic1, UBQLN1, UBQN, XDRP1, Xdrp1Protein level used designations for Ubiquilin 1
- ubiquilin-1
- ubiquilin 1
- ubiquilin-1-like
- hPLIC-1
- protein linking IAP with cytoskeleton 1
- PLIC-1
Did you look for something else?
- Ubinuclein 1
- UBIM
- UBIAD1
- UBFD1
- UBE4B
- UBE4A
- UBE3D
- UBE3C
- UBE3B
- ube3a
- UBE2Z
- UBE2W
- UBE2V2
- UBE2V1
- UBE2U
- Ube2t
- UBE2S.2
- UBE2R2
- UBE2QL1
- UBE2Q2L
- Ubiquilin 2
- Ubiquilin 3
- Ubiquinol-Cytochrome C Reductase Complex Assembly Factor 3
- Ubiquinol-Cytochrome C Reductase Complex Chaperone
- Ubiquinol-Cytochrome C Reductase Core Protein II
- Ubiquitin
- Ubiquitin +1
- Ubiquitin 11
- Ubiquitin Associated Protein 1
- Ubiquitin B
- Ubiquitin Specific Peptidase 12
- Ubiquitin-Conjugating Enzyme E2D 3
- Ubiquitin-Conjugating Enzyme E2E 3
- Ubiquitin-Conjugating Enzyme E2G 2
- Ubiquitin-Conjugating Enzyme E2I
- Ubiquitin-Conjugating Enzyme E2K
- Ubiquitin-Conjugating Enzyme E2N
- Ubiquitin-Conjugating Enzyme E2S
- UBL3
- UBL4A
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