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UBE4B Products

(Ubiquitin Conjugation Factor E4 B (UBE4B))

Categories

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured UBE4B Categories

UBE4B Antibodies

High quality antibodies with extensive validation data.

UBE4B Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended UBE4B Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (4)
Cat. No. ABIN388841
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), IF, ICC
Validations
  • (3)
Cat. No. ABIN2856674
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7254670
Quantity 200 μL
Datasheet Datasheet

Recommended UBE4B ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6208295
Quantity 96 tests
Datasheet Datasheet

Recommended UBE4B Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324436
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3096167
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3137220
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our UBE4B products

Periz, Lu, Zhang, Kankel, Jablonski, Kalb, McCampbell, Wang: "Regulation of protein quality control by UBE4B and LSD1 through p53-mediated transcription." in: PLoS biology, Vol. 13, Issue 4, pp. e1002114, (2015) (PubMed).

Arabi, Ullah, Branca, Johansson, Bandarra, Haneklaus, Fu, Ariës, Nilsson, Den Boer, Pokrovskaja, Grandér, Xiao, Rocha, Lehtiö, Sangfelt: "Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway." in: Nature communications, Vol. 3, pp. 976, (2012) (PubMed).

Mahoney, Odin, White, Shaffer, Koff, Casciola-Rosen, Rosen: "The human homologue of the yeast polyubiquitination factor Ufd2p is cleaved by caspase 6 and granzyme B during apoptosis." in: The Biochemical journal, Vol. 361, Issue Pt 3, pp. 587-95, (2002) (PubMed).

Synonyms and alternative names related to UBE4B

ubiquitination factor E4B (Ube4b), putative ubiquitin conjugation factor E4 B (LINJ_30_1070), putative ubiquitin conjugation factor E4 B (LBRM_30_1130), ubiquitin conjugation factor E4 B (Tsp_12732), ubiquitin conjugation factor E4 B (Tsp_01624), ubiquitination factor E4B, UFD2 homolog (S. cerevisiae) (ube4b), ubiquitination factor E4B (UBE4B), 4930551I19Rik, 4933406G05Rik, AU014668, D4Bwg0973e, E4, HDNB1, mKIAA0684, UBOX3, UFD2, ufd2a, UFD2A, UFD2a, Ufd2p

Protein level used designations for UBE4B

  • ubiquitin conjugation factor E4 B
  • ubiquitination factor E4B (UFD2 homolog, yeast)
  • ubiquitination factor E4B, UFD2 homolog
  • ubiquitin fusion degradation protein 2
  • UFD2A-III/UBE4B-III splice isoform
  • homologous to yeast UFD2
  • homozygously deleted in neuroblastoma 1
  • homozygously deleted in neuroblastoma-1
  • ubiquitin-fusion degradation protein 2
  • ubiquitination factor E4B (homologous to yeast UFD2)
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