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UBE3B Products

(Ubiquitin Protein Ligase E3B (UBE3B))

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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: E1 ubiquitin-activating enzymes, E2 ubiquitin-conjugating enzymes, and E3 ubiquitin-protein ligases. This gene encodes a member of the E3 ubiquitin-conjugating enzyme family which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme and transfers the ubiquitin to the targeted substrates. A HECT (homology to E6-AP C-terminus) domain in the C-terminus of the longer isoform of this protein is the catalytic site of ubiquitin transfer and forms a complex with E2 conjugases. Shorter isoforms of this protein which lack the C-terminal HECT domain are therefore unlikely to bind E2 enzymes. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2012].

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Featured UBE3B Categories

UBE3B Antibodies

High quality antibodies with extensive validation data.

UBE3B Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended UBE3B Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6265855
Quantity 100 μL
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN6740821
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN631147
Quantity 100 μL
Datasheet Datasheet

Recommended UBE3B Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324429
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
Cat. No. ABIN1324428
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3096166
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our UBE3B products

Kohlbrenner, Shaskan, Pietersen, Sonntag, Woo: "Gene expression profile associated with postnatal development of pyramidal neurons in the human prefrontal cortex implicates ubiquitin ligase E3 in the pathophysiology of schizophrenia onset." in: Journal of psychiatric research, Vol. 102, pp. 110-117, (2019) (PubMed).

Szafranski, Schindler, Taudien, Hiller, Huse, Jahn, Schreiber, Backofen, Platzer: "Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns." in: Genome biology, Vol. 8, Issue 8, pp. R154, (2008) (PubMed).

Synonyms and alternative names related to UBE3B

ubiquitin protein ligase E3B (UBE3B), ubiquitin protein ligase E3B (ube3b), ubiquitin-protein ligase E3B (LOC581811), ubiquitin protein ligase E3B L homeolog (ube3b.L), ubiquitin protein ligase E3B (Ube3b), AI449831, AU020130, BPIDS, si:dkey-189p24.3

Protein level used designations for UBE3B

  • ubiquitin-protein ligase E3B
  • ubiquitin protein ligase E3B
  • ubiquitin-protein ligase E3B-like
  • ubiquitin protein ligase E3
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