UBA2 Products
(SUMO1 Activating Enzyme Subunit 2 (UBA2))
Categories
Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1\; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010].
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Featured UBA2 Categories
UBA2 Antibodies
High quality antibodies with extensive validation data.
UBA2 ELISA Kits
Reliable ELISA kits for a wide range of species.
UBA2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended UBA2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (6)
Cat. No.
ABIN5692937
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p)
Validations
- (5)
Cat. No.
ABIN5708279
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (3)
- (2)
Cat. No.
ABIN1944808
Quantity
100 μg
Datasheet
Datasheet
Recommended UBA2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1381576
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN421748
Quantity
96 tests
Datasheet
Datasheet
Recommended UBA2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324292
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
- (1)
Cat. No.
ABIN6387816
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7422214
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our UBA2 products
: "Shigella infection interferes with SUMOylation and increases PML-NB number." in: PLoS ONE, Vol. 10, Issue 4, pp. e0122585, (2015) (PubMed).: "Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure." in: Nature communications, Vol. 6, pp. 7229, (2015) (PubMed).
: "High-yield expression of mouse Aos1-Uba2-fusion SUMO-activating enzyme, mAU, in a baculovirus-insect cell system." in: Bioscience, biotechnology, and biochemistry, Vol. 77, Issue 7, pp. 1575-8, (2013) (PubMed).
: "Influenza A virus interacts extensively with the cellular SUMOylation system during infection." in: Virus research, Vol. 158, Issue 1-2, pp. 12-27, (2011) (PubMed).
: "Developmental control of sumoylation pathway proteins in mouse male germ cells." in: Developmental biology, Vol. 321, Issue 1, pp. 227-37, (2008) (PubMed).
: "NXP-2 association with SUMO-2 depends on lysines required for transcriptional repression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 14, pp. 5308-13, (2006) (PubMed).
: "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. ..." in: Genome research, Vol. 11, Issue 3, pp. 422-35, (2001) (PubMed).
: "In vitro SUMO-1 modification requires two enzymatic steps, E1 and E2." in: Biochemical and biophysical research communications, Vol. 254, Issue 3, pp. 693-8, (1999) (PubMed).
: "Molecular cloning and characterization of human AOS1 and UBA2, components of the sentrin-activating enzyme complex." in: FEBS letters, Vol. 448, Issue 1, pp. 185-9, (1999) (PubMed).
: "Identification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1." in: The Journal of biological chemistry, Vol. 274, Issue 15, pp. 10618-24, (1999) (PubMed).
Synonyms and alternative names related to UBA2
SUMO1 activating enzyme subunit 2 (MICPUN_63834), SUMO1 activating enzyme subunit 2 (MICPUCDRAFT_36729), SUMO-activating enzyme 2 (SAE2), ubiquitin like modifier activating enzyme 2 (UBA2), ubiquitin-like modifier activating enzyme 2 (Uba2), ubiquitin like modifier activating enzyme 2 L homeolog (uba2.L), ubiquitin-like modifier activating enzyme 2 (uba2), AA986091, ARX, Arx, ATSAE2, EMB2764, EMBRYO DEFECTIVE 2764, F3K23.23, F3K23_23, SAE2, Sae2, sae2, sae2-B, sae2b, SUMO-ACTIVATING ENZYME 2, SUMO-activating enzyme 2, UBA1, uba2-a, uba2-b, Ubl1a2, Uble1b, uble1b, uble1b-B, wu:fi17g06, zgc:66354Protein level used designations for UBA2
- SUMO1 activating enzyme subunit 2
- SUMO-1 activating enzyme subunit 2
- SUMO-activating enzyme subunit 2
- UBA2, ubiquitin-activating enzyme E1 homolog
- anthracycline-associated resistance ARX
- ubiquitin-like 1-activating enzyme E1B
- Sumo-1 activating enzyme subunit 2
- ubiquitin-like 1 (sentrin) activating enzyme E1B
- ubiquitin-like 1 (sentrin) activating enzyme subunit 2
- SUMO-activating enzyme subunit 2-A
- SUMO-activating enzyme subunit 2-B
- ubiquitin-like 1-activating enzyme E1B-A
- ubiquitin-like 1-activating enzyme E1B-B
- SUMO1 activating enzyme subunit 2b
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