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TXNRD2 Products

(Thioredoxin Reductase 2 (TXNRD2))
Thioredoxin reductase (TR) is a dimeric NADPH-dependent FAD containing enzyme that catalyzes the reduction of the active site disulfide of thioredoxin and other substrates. TR is a member of a family of pyridine nucleotide-disulfide oxidoreductases and is a key enzyme in the regulation of the intracellular redox environment. Three thioredoxin reductase genes have been found that encode selenocysteine containing proteins. This gene partially overlaps the COMT gene on chromosome 22. [provided by RefSeq, Jul 2008].

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Featured TXNRD2 Categories

TXNRD2 Antibodies

High quality antibodies with extensive validation data.

TXNRD2 ELISA Kits

Reliable ELISA kits for a wide range of species.

TXNRD2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TXNRD2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN6149741
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7172022
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (3)
Cat. No. ABIN6265762
Quantity 100 μL
Datasheet Datasheet

Recommended TXNRD2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6959912
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1381569
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5659158
Quantity 96 tests
Datasheet Datasheet

Recommended TXNRD2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324250
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5711914
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow
Source Yeast
Validations
Cat. No. ABIN1653713
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TXNRD2 products

Zaccaria, Curti, Di Lorenzo, Baldi, Maccario, Sommatis, Mocchi, Daglia: "Effect of Green and Brown Propolis Extracts on the Expression Levels of microRNAs, mRNAs and Proteins, Related to Oxidative Stress and Inflammation." in: Nutrients, Vol. 9, Issue 10, (2018) (PubMed).

Okoh, Garba, Penney, Das, Deoraj, Singh, Sarkar, Felty, Yoo, Jackson, Roy: "Redox signalling to nuclear regulatory proteins by reactive oxygen species contributes to oestrogen-induced growth of breast cancer cells." in: British journal of cancer, Vol. 112, Issue 10, pp. 1687-702, (2015) (PubMed).

Touat-Hamici, Legrain, Bulteau, Chavatte: "Selective up-regulation of human selenoproteins in response to oxidative stress." in: The Journal of biological chemistry, Vol. 289, Issue 21, pp. 14750-61, (2014) (PubMed).

Wirth, Sheu, Chiu-Ugalde, Sapin, Klein, Mossbrugger, Quintanilla-Martinez, de Angelis, Krude, Riebel, Rothe, Köhrle, Schmid, Schweizer, Grüters: "Monocarboxylate transporter 8 deficiency: altered thyroid morphology and persistent high triiodothyronine/thyroxine ratio after thyroidectomy." in: European journal of endocrinology, Vol. 165, Issue 4, pp. 555-61, (2011) (PubMed).

Wirth, Conrad, Winterer, Wozny, Carlson, Roth, Schmitz, Bornkamm, Coppola, Tessarollo, Schomburg, Köhrle, Hatfield, Schweizer: "Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegeneration." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 3, pp. 844-52, (2010) (PubMed).

Dammeyer, Arnér: "Human Protein Atlas of redox systems - what can be learnt?" in: Biochimica et biophysica acta, Vol. 1810, Issue 1, pp. 111-38, (2010) (PubMed).

Mustacich, Powis: "Thioredoxin reductase." in: The Biochemical journal, Vol. 346 Pt 1, pp. 1-8, (2000) (PubMed).

Synonyms and alternative names related to TXNRD2

thioredoxin reductase 2 (Trxr-2), thioredoxin reductase 2 (TXNRD2), thioredoxin reductase 2 (Txnrd2), AA118373, CG11401, Dm-TrxR, Dmel\\CG11401, DmTrx, DmTrxR-2, ESTM573010, SELZ, TGR, TR, TR-BETA, TR3, Tr3, trxr-2, Trxr2, TRXR2, Trxrd2

Protein level used designations for TXNRD2

  • CG11401-PA
  • Trxr-2-PA
  • thioredoxin reductase
  • thioredoxin-reductase-2
  • selenoprotein Z
  • thioredoxin reductase 2, mitochondrial
  • thioredoxin reductase 3
  • thioredoxin reductase TR3
  • thioredoxin reductase beta
  • TR beta
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