TXNRD1 Products
(Thioredoxin Reductase 1 (TXNRD1))
Categories
This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. [provided by RefSeq, Jul 2008].
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Featured TXNRD1 Categories
TXNRD1 Antibodies
High quality antibodies with extensive validation data.
TXNRD1 ELISA Kits
Reliable ELISA kits for a wide range of species.
TXNRD1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TXNRD1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7432433
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (1)
- (4)
Cat. No.
ABIN1386102
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, ICC, IHC (p)
Validations
- (5)
Cat. No.
ABIN2855577
Quantity
100 μL
Datasheet
Datasheet
Recommended TXNRD1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962389
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959909
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959910
Quantity
96 tests
Datasheet
Datasheet
Recommended TXNRD1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324248
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125363
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7391732
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our TXNRD1 products
: "Relationship between selenoprotein P and selenocysteine lyase: Insights into selenium metabolism." in: Free radical biology & medicine, Vol. 127, pp. 182-189, (2018) (PubMed).: "Monitoring thioredoxin redox with a genetically encoded red fluorescent biosensor." in: Nature chemical biology, Vol. 13, Issue 9, pp. 1045-1052, (2017) (PubMed).
: "Intratumoral hemorrhage-related differences in the expression of vascular endothelial growth factor, basic fibroblast growth factor and thioredoxin reductase 1 in human glioblastoma." in: Molecular and clinical oncology, Vol. 5, Issue 4, pp. 343-346, (2016) (PubMed).
: "The Cellular Thioredoxin-1/Thioredoxin Reductase-1 Driven Oxidoreduction Represents a Chemotherapeutic Target for HIV-1 Entry Inhibition." in: PLoS ONE, Vol. 11, Issue 1, pp. e0147773, (2016) (PubMed).
: "Thioredoxin reductase as a novel molecular target for cancer therapy." in: Cancer letters, Vol. 236, Issue 2, pp. 164-74, (2006) (PubMed).
: "On the potential of thioredoxin reductase inhibitors for cancer therapy." in: Seminars in cancer biology, Vol. 16, Issue 6, pp. 452-65, (2006) (PubMed).
: "Thioredoxin reductase." in: The Biochemical journal, Vol. 346 Pt 1, pp. 1-8, (2000) (PubMed).
: "Cloning and sequencing of a human thioredoxin reductase." in: FEBS letters, Vol. 373, Issue 1, pp. 5-9, (1995) (PubMed).
Synonyms and alternative names related to TXNRD1
thioredoxin reductase 1 (TXNRD1), thioredoxin reductase 1 (txnrd1), thioredoxin reductase 1 (Trxr-1), thioredoxin reductase 1 L homeolog (txnrd1.L), NADPH-dependent thioredoxin reductase C (NTRC), ThioRedoXin Reductase (trxr-1), thioredoxin reductase 1 (Txnrd1), cb682, fb83a08, GB14972, GRIM-12, MGC85342, NADPH-dependent thioredoxin reductase C, T32G6.20, T32G6_20, TR, Tr, TR1, TrxR1, TRXR1, TXNR, wu:fb83a08Protein level used designations for TXNRD1
- thioredoxin reductase 1, cytoplasmic
- thioredoxin reductase 3
- thioredoxin reductase 1
- thioredoxin reductase 1, cytoplasmic-like
- KM-102-derived reductase-like factor
- gene associated with retinoic and IFN-induced mortality 12 protein
- gene associated with retinoic and interferon-induced mortality 12 protein
- oxidoreductase
- thioredoxin reductase GRIM-12
- thioredoxin reductase TR1
- TR
- redox enzyme thioredoxin reductase
- NADPH-dependent thioredoxin reductase
- selenoprotein oxidoreductase
- TR alpha
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