Tuberin Products
(Tuberous Sclerosis 2 (TSC2))
Categories
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Featured Tuberin Categories
Tuberin Antibodies
High quality antibodies with extensive validation data.
Tuberin ELISA Kits
Reliable ELISA kits for a wide range of species.
Recommended Tuberin Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p)
Validations
- (5)
Cat. No.
ABIN390324
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (7)
Cat. No.
ABIN3043498
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (1)
- (3)
Cat. No.
ABIN701200
Quantity
100 μL
Datasheet
Datasheet
Recommended Tuberin ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970922
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970921
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380275
Quantity
2 x 96 tests
Datasheet
Datasheet
Recommended Tuberin Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1323848
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our Tuberin products
: "Repression of TSC1/TSC2 mediated by MeCP2 regulates human embryo lung fibroblast cell differentiation and proliferation." in: International journal of biological macromolecules, Vol. 96, pp. 578-588, (2017) (PubMed).: "PP2AC Level Determines Differential Programming of p38-TSC-mTOR Signaling and Therapeutic Response to p38-Targeted Therapy in Colorectal Cancer." in: EBioMedicine, Vol. 2, Issue 12, pp. 1944-56, (2016) (PubMed).
: "Regulation of the mTOR signaling network in hibernating thirteen-lined ground squirrels." in: The Journal of experimental biology, Vol. 215, Issue Pt 10, pp. 1720-7, (2012) (PubMed).
: "Phospho-?Np63?/Rpn13-dependent regulation of LKB1 degradation modulates autophagy in cancer cells." in: Aging, Vol. 2, Issue 12, pp. 959-68, (2011) (PubMed).
: "Zebrafish Thsd7a is a neural protein required for angiogenic patterning during development." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 240, Issue 6, pp. 1412-21, (2011) (PubMed).
: "Amplification of the angiogenic signal through the activation of the TSC/mTOR/HIF axis by the KSHV vGPCR in Kaposi's sarcoma." in: PLoS ONE, Vol. 6, Issue 4, pp. e19103, (2011) (PubMed).
: "Mechanism of photooxidation of folic acid sensitized by unconjugated pterins." in: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, Vol. 9, Issue 12, pp. 1604-12, (2010) (PubMed).
: "Tuberous sclerosis complex 2 (TSC2) regulates cell migration and polarity through activation of CDC42 and RAC1." in: The Journal of biological chemistry, Vol. 285, Issue 32, pp. 24987-98, (2010) (PubMed).
: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).
: "Tuberous sclerosis complex activity is required to control neuronal stress responses in an mTOR-dependent manner." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 18, pp. 5926-37, (2009) (PubMed).
Synonyms and alternative names related to Tuberin
TSC complex subunit 2 (TSC2), tuberin (LOC5569538), TSC complex subunit 2 (tsc2), hypothetical protein (PGTG_00159), tuberous sclerosis 2 (Tsc2), TSC complex subunit 2 (Tsc2), tuberous sclerosis 2 (TSC2), fc16b02, LAM, Nafld, Rc, Tcs2, TSC2, TSC4, tuberin, wu:fc16b02Protein level used designations for Tuberin
- tuberous sclerosis complex 2 (TSC2)
- tuberous sclerosis 2
- tuberin-like
- tuberin
- tuberous sclerosis 2 protein
- tuberous sclerosis 2 protein homolog
- renal carcinoma
- tuberous sclerosis 2 homolog protein
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