TTR Products
(Transthyretin (TTR))
Categories
This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein\; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported\; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. [provided by RefSeq, Jan 2009].
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Featured TTR Categories
TTR Antibodies
High quality antibodies with extensive validation data.
TTR ELISA Kits
Reliable ELISA kits for a wide range of species.
TTR Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TTR Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, ICC, FACS
Validations
- (7)
Cat. No.
ABIN5542369
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (1)
- (5)
Cat. No.
ABIN3021474
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7429271
Quantity
100 μL
Datasheet
Datasheet
Recommended TTR ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (7)
- (6)
Cat. No.
ABIN6574196
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6960157
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN7041488
Quantity
96 tests
Datasheet
Datasheet
Recommended TTR Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275811
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275810
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125488
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our TTR products
: "Normal Neurodevelopment and Fertility in Juvenile Male Rats Exposed to Polyethylene Glycol Following Dosing With PEGylated rFIX (Nonacog Beta Pegol, N9-GP): Evidence from a 10-Week Repeat-Dose ..." in: International journal of toxicology, Vol. 41, Issue 6, pp. 455-475, (2022) (PubMed).: "Identification and characterization of antigen-specific CD4+ T cells targeting renally expressed antigens in human lupus nephritis with two independent methods." in: Scientific reports, Vol. 10, Issue 1, pp. 21312, (2020) (PubMed).
: "CD4+ T Cells Affect the Thyroid Hormone Transport at the Choroid Plexus in Mice Raised in Enriched Environment." in: Neuroimmunomodulation, Vol. 26, Issue 2, pp. 59-66, (2020) (PubMed).
: "Primary Cardiac Involvement in the Rare Transthyretin Ile73Val Mutation: A Case Series." in: Circulation. Genomic and precision medicine, Vol. 13, Issue 3, pp. e002792, (2020) (PubMed).
: "iTRAQ-Based Quantitative Proteomics Reveals the New Evidence Base for Traumatic Brain Injury Treated with Targeted Temperature Management." in: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, Vol. 15, Issue 1, pp. 216-232, (2019) (PubMed).
: "Connective Tissue Growth Factor Promotes Efficient Generation of Human Induced Pluripotent Stem Cell-Derived Choroidal Endothelium." in: Stem cells translational medicine, Vol. 6, Issue 6, pp. 1533-1546, (2019) (PubMed).
: "CellSIUS provides sensitive and specific detection of rare cell populations from complex single-cell RNA-seq data." in: Genome biology, Vol. 20, Issue 1, pp. 142, (2019) (PubMed).
: "LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration. ..." in: Nature, Vol. 562, Issue 7728, pp. 605-609, (2019) (PubMed).
: "Zika Virus Infection in Hypothalamus Causes Hormone Deficiencies and Leads to Irreversible Growth Delay and Memory Impairment in Mice." in: Cell reports, Vol. 25, Issue 6, pp. 1537-1547.e4, (2018) (PubMed).
: "Tetraiodothyroacetic acid and transthyretin silencing inhibit pro-metastatic effect of L-thyroxin in anoikis-resistant prostate cancer cells through regulation of MAPK/ERK pathway." in: Experimental cell research, Vol. 347, Issue 2, pp. 350-9, (2017) (PubMed).
Synonyms and alternative names related to TTR
transthyretin (prealbumin, amyloidosis type I) (ttr), transthyretin (TTR), transthyretin (vpb38), transthyretin (MRAD2831_RS38185), Transthyretin (Caci_4246), transthyretin (prealbumin, amyloidosis type 1) (ttr), transthyretin-like (LOC100226992), transthyretin (Ttr), transthyretin L homeolog (ttr.L), AA408768, AI787086, CTS, CTS1, D17860, HsT2651, LOC100226992, Lr1, PALB, prealbumin, Prealbumin, TBPA, Tbpa, TTR, xTTR, zgc:103583Protein level used designations for TTR
- transthyretin
- transthyretin (prealbumin, amyloidosis type I)
- Transthyretin
- transthyretin (prealbumin, amyloidosis type 1)
- ATTR
- carpal tunnel syndrome 1
- prealbumin, amyloidosis type I
- thyroxine-binding prealbumin
- TBPA
- prealbumin
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