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TTI1 Products

(TELO2 Interacting Protein 1 (TTI1))

Categories

Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.

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Featured TTI1 Categories

TTI1 Antibodies

High quality antibodies with extensive validation data.

TTI1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TTI1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7171701
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7244333
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN651167
Quantity 400 μL
Datasheet Datasheet

Recommended TTI1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6234814
Quantity 96 tests
Datasheet Datasheet

Recommended TTI1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3096143
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3136774
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (1)
Cat. No. ABIN5505782
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our TTI1 products

You, Sobreira, Gable, Jurgens, Grange, Belnap, Siniard, Szelinger, Schrauwen, Richholt, Vallee, Dinulos, Valle, Armanios, Hoover-Fong: "A Syndromic Intellectual Disability Disorder Caused by Variants in TELO2, a Gene Encoding a Component of the TTT Complex." in: American journal of human genetics, Vol. 98, Issue 5, pp. 909-18, (2016) (PubMed).

Synonyms and alternative names related to TTI1

TELO2 interacting protein 1 (TTI1), TELO2 interacting protein 1 (Tti1), 2610036D13Rik, AI449463, KIAA0406, RGD1562582, smg-10

Protein level used designations for TTI1

  • TEL2-interacting protein 1 homolog
  • TELO2-interacting protein 1 homolog
  • Tel two interacting protein 1
  • Tel2 interacting protein 1 homolog
  • smg-10 homolog, nonsense mediated mRNA decay factor
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