TTI1 Products
(TELO2 Interacting Protein 1 (TTI1))
Categories
Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.
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Featured TTI1 Categories
TTI1 Antibodies
High quality antibodies with extensive validation data.
TTI1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TTI1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7171701
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7244333
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN651167
Quantity
400 μL
Datasheet
Datasheet
Recommended TTI1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6234814
Quantity
96 tests
Datasheet
Datasheet
Recommended TTI1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3096143
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3136774
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Insect cells (Sf9)
Validations
- (1)
Cat. No.
ABIN5505782
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our TTI1 products
: "A Syndromic Intellectual Disability Disorder Caused by Variants in TELO2, a Gene Encoding a Component of the TTT Complex." in: American journal of human genetics, Vol. 98, Issue 5, pp. 909-18, (2016) (PubMed).Synonyms and alternative names related to TTI1
TELO2 interacting protein 1 (TTI1), TELO2 interacting protein 1 (Tti1), 2610036D13Rik, AI449463, KIAA0406, RGD1562582, smg-10Protein level used designations for TTI1
- TEL2-interacting protein 1 homolog
- TELO2-interacting protein 1 homolog
- Tel two interacting protein 1
- Tel2 interacting protein 1 homolog
- smg-10 homolog, nonsense mediated mRNA decay factor
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