TSH receptor Products
(Thyroid Stimulating Hormone Receptor (TSHR))
Categories
The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008].
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Featured TSH receptor Categories
TSH receptor Antibodies
High quality antibodies with extensive validation data.
TSH receptor ELISA Kits
Reliable ELISA kits for a wide range of species.
TSH receptor Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TSH receptor Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (1)
- (5)
Cat. No.
ABIN6149622
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, FACS, IHC (p)
Validations
- (5)
Cat. No.
ABIN668901
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bacteria, Human, Rat
Application
ELISA, IHC (p)
Validations
- (4)
Cat. No.
ABIN723470
Quantity
100 μL
Datasheet
Datasheet
Recommended TSH receptor ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970681
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959969
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Goat
Analytical Method
Validations
Cat. No.
ABIN996270
Quantity
96 tests
Datasheet
Datasheet
Recommended TSH receptor Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7491755
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125394
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (2)
Cat. No.
ABIN1330596
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our TSH receptor products
: "Generation and characterization of a hypothyroidism rat model with truncated thyroid stimulating hormone receptor." in: Scientific reports, Vol. 8, Issue 1, pp. 4004, (2018) (PubMed).: "Thyrotropin Receptor Antibody (TRAb)-IgM Levels Are Markedly Higher Than TRAb-IgG Levels in Graves' Disease Patients and Controls, and TRAb-IgM Production Is Related to Epstein-Barr Virus ..." in: Viral immunology, Vol. 29, Issue 8, pp. 459-463, (2016) (PubMed).
: "Reactivation of persistent Epstein-Barr virus (EBV) causes secretion of thyrotropin receptor antibodies (TRAbs) in EBV-infected B lymphocytes with TRAbs on their surface." in: Autoimmunity, Vol. 48, Issue 5, pp. 328-35, (2015) (PubMed).
: "Semiquantitative immunohistochemical marker staining and localization in canine thyroid carcinoma and normal thyroid gland." in: Veterinary and comparative oncology, (2014) (PubMed).
: "Subclinical nonautoimmune hyperthyroidism in a family segregates with a thyrotropin receptor mutation with weakly increased constitutive activity." in: Thyroid : official journal of the American Thyroid Association, Vol. 20, Issue 11, pp. 1307-14, (2010) (PubMed).
: "[Massive hemoptysis due to traction bronchiectasis caused by thoracic radiotherapy 23 years earlier]" in: Kyobu geka. The Japanese journal of thoracic surgery, Vol. 61, Issue 3, pp. 226-9, (2008) (PubMed).
: "Structural determinants for g protein activation and selectivity in the second intracellular loop of the thyrotropin receptor." in: Endocrinology, Vol. 146, Issue 1, pp. 477-85, (2004) (PubMed).
: "Regulation of the phosphatidylinositol 3-kinase, Akt/protein kinase B, FRAP/mammalian target of rapamycin, and ribosomal S6 kinase 1 signaling pathways by thyroid-stimulating hormone (TSH) and ..." in: The Journal of biological chemistry, Vol. 278, Issue 24, pp. 21960-71, (2003) (PubMed).
: "Thyroid-stimulating autoantibodies in Graves disease preferentially recognize the free A subunit, not the thyrotropin holoreceptor." in: The Journal of clinical investigation, Vol. 110, Issue 2, pp. 209-17, (2002) (PubMed).
: "Cloning, chromosomal assignment, and regulation of the rat thyrotropin receptor: expression of the gene is regulated by thyrotropin, agents that increase cAMP levels, and thyroid autoantibodies." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 15, pp. 5677-81, (1990) (PubMed).
Synonyms and alternative names related to TSH receptor
thyroid stimulating hormone receptor (tshr), thyroid stimulating hormone receptor (TSHR), thyroid stimulating hormone receptor (Tshr), AI481368, CHNG1, hTSHR-I, hypothroid, hyt, LGR3, pet, TSH-R, TSHRAProtein level used designations for TSH receptor
- TSH receptor
- thyroid-stimulating hormone receptor
- thyrotropin receptor
- seven transmembrane helix receptor
- thyrotropin receptor-I, hTSHR-I
- TSH-R
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