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TSG101 Products

(Tumor Susceptibility Gene 101 (TSG101))

Categories

The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008].

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Featured TSG101 Categories

TSG101 Antibodies

High quality antibodies with extensive validation data.

TSG101 ELISA Kits

Reliable ELISA kits for a wide range of species.

TSG101 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TSG101 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p), RNAi
Validations
  • (2)
  • (7)
Cat. No. ABIN563269
Quantity 100 μg
Datasheet Datasheet
Reactivity Fish, Human, Mouse, Rat
Application WB, ELISA, IHC (p), IF (cc), IHC (fro), IF (p)
Validations
  • (7)
Cat. No. ABIN685507
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB, IHC
Validations
  • (5)
  • (5)
Cat. No. ABIN2780037
Quantity 100 μL
Datasheet Datasheet

Recommended TSG101 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960315
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6974963
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5659699
Quantity 96 tests
Datasheet Datasheet

Recommended TSG101 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323883
Quantity 2 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1785917
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323884
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our TSG101 products

Bychkov, Kirichenko, Mikhaylova, Paramonov, Yastremsky, Kirpichnikov, Shulepko, Lyukmanova: "Extracellular Vesicles Derived from Acidified Metastatic Melanoma Cells Stimulate Growth, Migration, and Stemness of Normal Keratinocytes." in: , Vol. 10, Issue 3, (2022) (PubMed).

Bychkov, Kirichenko, Mikhaylova, Paramonov, Kirpichnikov, Shulepko, Lyukmanova: "Extracellular Vesicles Derived from Metastatic Melanoma Cells Transfer α7-nAChR mRNA, Thus Increasing the Surface Expression of the Receptor and Stimulating the Growth of Normal Keratinocytes." in: Acta naturae, Vol. 14, Issue 3, pp. 95-99, (2022) (PubMed).

Keysberg, Hertel, Schelletter, Busche, Sochart, Kalinowski, Hoffrogge, Otte, Noll: "Exploring the molecular content of CHO exosomes during bioprocessing." in: Applied microbiology and biotechnology, Vol. 105, Issue 9, pp. 3673-3689, (2021) (PubMed).

Murdica, Giacomini, Alteri, Bartolacci, Cermisoni, Zarovni, Papaleo, Montorsi, Salonia, Viganò, Vago: "Seminal plasma of men with severe asthenozoospermia contain exosomes that affect spermatozoa motility and capacitation." in: Fertility and sterility, Vol. 111, Issue 5, pp. 897-908.e2, (2019) (PubMed).

Haney, Klyachko, Harrison, Zhao, Kabanov, Batrakova: "TPP1 Delivery to Lysosomes with Extracellular Vesicles and their Enhanced Brain Distribution in the Animal Model of Batten Disease." in: Advanced healthcare materials, Vol. 8, Issue 11, pp. e1801271, (2019) (PubMed).

Minaidou, Nicolaou, Christodoulou: "Deregulation of LRSAM1 expression impairs the levels of TSG101, UBE2N, VPS28, MDM2 and EGFR." in: PLoS ONE, Vol. 14, Issue 2, pp. e0211814, (2019) (PubMed).

Uygur, Melikov, Arakelyan, Margolis, Chernomordik: "Syncytin 1 dependent horizontal transfer of marker genes from retrovirally transduced cells." in: Scientific reports, Vol. 9, Issue 1, pp. 17637, (2019) (PubMed).

Hon, Ab-Mutalib, Abdullah, Jamal, Abu: "Extracellular Vesicle-derived circular RNAs confers chemoresistance in Colorectal cancer." in: Scientific reports, Vol. 9, Issue 1, pp. 16497, (2019) (PubMed).

Guix, Corbett, Cha, Mustapic, Liu, Mengel, Chen, Aikawa, Young-Pearse, Kapogiannis, Selkoe, Walsh: "Detection of Aggregation-Competent Tau in Neuron-Derived Extracellular Vesicles." in: International journal of molecular sciences, Vol. 19, Issue 3, (2018) (PubMed).

Hough, Wilson, Trevor, Strenkowski, Maina, Kim, Spell, Wang, Chanda, Dager, Sharma, Curtiss, Antony, Dransfield, Chaplin, Steele, Barnes, Duncan, Prasain, Thannickal, Deshane: "Unique Lipid Signatures of Extracellular Vesicles from the Airways of Asthmatics." in: Scientific reports, Vol. 8, Issue 1, pp. 10340, (2018) (PubMed).

Synonyms and alternative names related to TSG101

tumor susceptibility 101 (TSG101), Tumor susceptibility gene 101 (TSG101), Tumor Susceptibility Gene homolog (tsg-101), tumor susceptibility 101 (tsg101), tumor susceptibility gene 101 (Tsg101), tumor susceptibility gene 101 (TSG101), tumor susceptibility 101 (Tsg101), tumor susceptibility 101a (tsg101a), tumor susceptibility 101 L homeolog (tsg101.L), AI255943, burs, CC2, CG9712, Dmel\\CG9712, DmTSG101, dTSg101, dTsg101, dVps23, ept, ESCRT-I, MGC76193, Rw, TSG10, Tsg101, tsg101, TSG101, vps23, VPS23, zgc:86926

Protein level used designations for TSG101

  • CG9712-PA
  • TSG101-PA
  • erupted
  • tumor susceptibility Gene-101
  • Tumor Susceptibility Gene homolog family member (tsg-101)
  • ESCRT-I complex subunit TSG101
  • tumor susceptibility gene 101 protein
  • tumor susceptibility protein 101
  • tumor susceptibility gene 101
  • tumor susceptibility gene 10
  • tumor susceptibility protein
  • Tumor supressor
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