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TSC1 Products

(Tuberous Sclerosis 1 (TSC1))
This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009].

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Featured TSC1 Categories

TSC1 Antibodies

High quality antibodies with extensive validation data.

TSC1 ELISA Kits

Reliable ELISA kits for a wide range of species.

TSC1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TSC1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (9)
Cat. No. ABIN1491685
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (1)
  • (5)
Cat. No. ABIN6149609
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB, IHC, IF, ICC
Validations
  • (5)
Cat. No. ABIN6265766
Quantity 100 μL
Datasheet Datasheet

Recommended TSC1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5690964
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1136087
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1136088
Quantity 96 tests
Datasheet Datasheet

Recommended TSC1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125518
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323846
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3096113
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TSC1 products

Zheng, Zhou, Zhang, Thu, Xie, Lu, Pang, Xue, Xu, Chen, Chen, Li, Xu: "Anhydroicaritin improves diet-induced obesity and hyperlipidemia and alleviates insulin resistance by suppressing SREBPs activation." in: Biochemical pharmacology, Vol. 122, pp. 42-61, (2017) (PubMed).

Qin, Zheng, Zhou, Ou, Huang, Yan, Qin, Yang, Su, Bai, Guo, Lin: "Tsc1 deficiency impairs mammary development in mice by suppression of AKT, nuclear ERα, and cell-cycle-driving proteins." in: Scientific reports, Vol. 6, pp. 19587, (2017) (PubMed).

Zhang, Wang, Qin, Wang, Liu, White, Zheng: "PP2AC Level Determines Differential Programming of p38-TSC-mTOR Signaling and Therapeutic Response to p38-Targeted Therapy in Colorectal Cancer." in: EBioMedicine, Vol. 2, Issue 12, pp. 1944-56, (2016) (PubMed).

Cao, Wei, Liu, Wang, Wu, Xie, Capellini, Zhang, Zhao, Li, Zhong, Wang, Lu, Liu, Zhang, Du, Zhang, Du: "DNA methylation Landscape of body size variation in sheep." in: Scientific reports, Vol. 5, pp. 13950, (2016) (PubMed).

Zhao, Zhao, Poage, Mazumdar, Zhang, Hill, Hartman, Savage, Mills, Brown: "Death-associated protein kinase 1 promotes growth of p53-mutant cancers." in: The Journal of clinical investigation, Vol. 125, Issue 7, pp. 2707-20, (2015) (PubMed).

Mehta, Vazquez, Kulkarni, Kerrigan, Atwal, Metsugi, Toppmeyer, Levine, Hirshfield: "Polymorphic variants in TSC1 and TSC2 and their association with breast cancer phenotypes." in: Breast cancer research and treatment, Vol. 125, Issue 3, pp. 861-8, (2011) (PubMed).

Bateup, Takasaki, Saulnier, Denefrio, Sabatini: "Loss of Tsc1 in vivo impairs hippocampal mGluR-LTD and increases excitatory synaptic function." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 24, pp. 8862-9, (2011) (PubMed).

Miceli, Saporita, Weber: "Hypergrowth mTORC1 signals translationally activate the ARF tumor suppressor checkpoint." in: Molecular and cellular biology, Vol. 32, Issue 2, pp. 348-64, (2011) (PubMed).

Synonyms and alternative names related to TSC1

TSC complex subunit 1 (TSC1), TSC complex subunit 1 (Tsc1), tuberous sclerosis 1 (Tsc1), tuberous sclerosis 1 (TSC1), TSC complex subunit 1b (tsc1b), TSC complex subunit 1 (tsc1), TSC complex subunit 1a (tsc1a), fa99f04, hamartin, LAM, mKIAA0243, TSC, tsc1, wu:fa99f04, wu:fc38b04, zgc:63657

Protein level used designations for TSC1

  • hamartin
  • tuberous sclerosis 1 protein
  • tumor suppressor
  • tuberous sclerosis 1 protein homolog
  • chromosome 9 TSC1
  • tuberous sclerosis 1
  • fc38b04
  • hamartin-like
  • tuberous sclerosis 1a
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