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TRRAP Products

(Transformation/transcription Domain-Associated Protein (TRRAP))

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This gene encodes a large multidomain protein of the phosphoinositide 3-kinase-related kinases (PIKK) family. The encoded protein is a common component of many histone acetyltransferase (HAT) complexes and plays a role in transcription and DNA repair by recruiting HAT complexes to chromatin. Deregulation of this gene may play a role in several types of cancer including glioblastoma multiforme. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011].

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Featured TRRAP Categories

TRRAP Antibodies

High quality antibodies with extensive validation data.

TRRAP ELISA Kits

Reliable ELISA kits for a wide range of species.

Recommended TRRAP Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN6243321
Quantity 200 μL
Datasheet Datasheet
Reactivity Mouse
Application WB
Validations
  • (1)
Cat. No. ABIN6243320
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC
Validations
  • (2)
Cat. No. ABIN5014439
Quantity 100 μL
Datasheet Datasheet

Recommended TRRAP ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1162674
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1162675
Quantity 96 tests
Datasheet Datasheet

Recommended TRRAP Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323838
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7417159
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our TRRAP products

Krebs, Demmers, Karmodiya, Chang, Chang, Tora: "ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes." in: EMBO reports, Vol. 11, Issue 7, pp. 541-7, (2010) (PubMed).

Szutorisz, Canzonetta, Georgiou, Chow, Tora, Dillon: "Formation of an active tissue-specific chromatin domain initiated by epigenetic marking at the embryonic stem cell stage." in: Molecular and cellular biology, Vol. 25, Issue 5, pp. 1804-20, (2005) (PubMed).

Liu, Tesfai, Evrard, Dent, Martinez: "c-Myc transformation domain recruits the human STAGA complex and requires TRRAP and GCN5 acetylase activity for transcription activation." in: The Journal of biological chemistry, Vol. 278, Issue 22, pp. 20405-12, (2003) (PubMed).

Lang, Hearing: "The adenovirus E1A oncoprotein recruits the cellular TRRAP/GCN5 histone acetyltransferase complex." in: Oncogene, Vol. 22, Issue 18, pp. 2836-41, (2003) (PubMed).

Hillier, Fulton, Fulton, Graves, Pepin, Wagner-McPherson, Layman, Maas, Jaeger, Walker, Wylie, Sekhon, Becker, OLaughlin, Schaller, Fewell, Delehaunty, Miner, Nash, Cordes, Du, Sun, Edwards et al.: "The DNA sequence of human chromosome 7. ..." in: Nature, Vol. 424, Issue 6945, pp. 157-64, (2003) (PubMed).

Synonyms and alternative names related to TRRAP

transformation/transcription domain associated protein (TRRAP), phosphotransferases/inositol or phosphatidylinositol kinase (AT4G36080), transcription-associated protein 1 (LOC5577036), transformation/transcription domain-associated protein (Trrap), transformation/transcription domain-associated protein (trrap), transformation/transcription domain associated protein (trrap), transformation/transcription domain-associated protein (TRRAP), transformation/transcription domain-associated protein (LOC100637779), AI481500, PAF350/400, PAF400, STAF40, TR-AP, Tra1, TRRAP, trrap

Protein level used designations for TRRAP

  • 350/400 kDa PCAF-associated factor
  • tra1 homolog
  • transformation/transcription domain-associated protein
  • transactivation/transformation-domain associated protein
  • transformation/transcription domain-associated protein-like
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