TRPM6 Products
(Transient Receptor Potential Cation Channel, Subfamily M, Member 6 (TRPM6))
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This gene is predominantly expressed in the kidney and colon, and encodes a protein containing an ion channel domain and a protein kinase domain. It is crucial for magnesium homeostasis, and plays an essential role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. Mutations in this gene are associated with hypomagnesemia with secondary hypocalcemia. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Apr 2010].
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Featured TRPM6 Categories
TRPM6 Antibodies
High quality antibodies with extensive validation data.
TRPM6 ELISA Kits
Reliable ELISA kits for a wide range of species.
TRPM6 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TRPM6 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
- (2)
Cat. No.
ABIN392616
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA, IF
Validations
- (2)
Cat. No.
ABIN7172868
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA, WB
Validations
- (3)
Cat. No.
ABIN3029237
Quantity
0.4 mL
Datasheet
Datasheet
Recommended TRPM6 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960126
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5674671
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5674672
Quantity
96 tests
Datasheet
Datasheet
Recommended TRPM6 Proteins
Latest Publications for our TRPM6 products
: "Up-Regulation of Transient Receptor Potential Melastatin 6 Channel Expression by Tumor Necrosis Factor-α in the Presence of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor." in: Journal of cellular physiology, Vol. 232, Issue 10, pp. 2841-2850, (2017) (PubMed).: "Renal adaptation to gentamicin-induced mineral loss." in: American journal of nephrology, Vol. 35, Issue 3, pp. 279-86, (2012) (PubMed).
: "Down-regulation of TRPM6-mediated magnesium influx by cyclosporin A." in: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 377, Issue 4-6, pp. 333-43, (2008) (PubMed).
: "TRPM6 expression and cell proliferation are up-regulated by phosphorylation of ERK1/2 in renal epithelial cells." in: Biochemical and biophysical research communications, Vol. 369, Issue 4, pp. 1129-33, (2008) (PubMed).
: "Phosphoinositide 3-kinase signalling pathways." in: Journal of cell science, Vol. 114, Issue Pt 8, pp. 1439-45, (2001) (PubMed).
: "Oncogenic kinase signalling." in: Nature, Vol. 411, Issue 6835, pp. 355-65, (2001) (PubMed).
: "The RET proto-oncogene in human cancers." in: Oncogene, Vol. 19, Issue 49, pp. 5590-7, (2000) (PubMed).
Synonyms and alternative names related to TRPM6
transient receptor potential cation channel subfamily M member 6 (TRPM6), transient receptor potential cation channel, subfamily M, member 6 (Trpm6), CHAK2, HMGX, HOMG, HOMG1, HSH, TRPM6, TRPM6/CHAK2Protein level used designations for TRPM6
- transient receptor potential cation channel, subfamily M, member 6
- channel kinase 2
- melastatin-related TRP cation channel 6
- transient receptor potential cation channel subfamily M member 6
- transient receptor potential cation channel 6/channel-kinase 2
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