TRPC6 Products
(Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6))
Categories
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq, Mar 2009].
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Featured TRPC6 Categories
TRPC6 Antibodies
High quality antibodies with extensive validation data.
TRPC6 ELISA Kits
Reliable ELISA kits for a wide range of species.
TRPC6 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TRPC6 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7441304
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (4)
Cat. No.
ABIN6149580
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, IHC (p)
Validations
- (1)
- (4)
Cat. No.
ABIN3044146
Quantity
100 μg
Datasheet
Datasheet
Recommended TRPC6 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960122
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5659481
Quantity
96 tests
Datasheet
Datasheet
Recommended TRPC6 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1323826
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7408279
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3135362
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our TRPC6 products
: "TRPC1/TRPC3 channels mediate lysophosphatidylcholine-induced apoptosis in cultured human coronary artery smooth muscles cells." in: Oncotarget, Vol. 7, Issue 32, pp. 50937-50951, (2018) (PubMed).: "Human Digital Meissner Corpuscles Display Immunoreactivity for the Multifunctional Ion Channels Trpc6 and Trpv4." in: Anatomical record (Hoboken, N.J. : 2007), Vol. 300, Issue 6, pp. 1022-1031, (2018) (PubMed).
: "Orai and TRPC channel characterization in FcεRI-mediated calcium signaling and mediator secretion in human mast cells." in: Physiological reports, Vol. 5, Issue 5, (2017) (PubMed).
: "Differences in TRPC3 and TRPC6 channels assembly in mesenteric vascular smooth muscle cells in essential hypertension." in: The Journal of physiology, (2016) (PubMed).
: "Mechanosensitive ATP release from hemichannels and Ca²⁺ influx through TRPC6 accelerate wound closure in keratinocytes." in: Journal of cell science, Vol. 127, Issue Pt 19, pp. 4159-71, (2014) (PubMed).
: "Opposing effects of podocin on the gating of podocyte TRPC6 channels evoked by membrane stretch or diacylglycerol." in: American journal of physiology. Cell physiology, Vol. 305, Issue 3, pp. C276-89, (2013) (PubMed).
: "NOX2 interacts with podocyte TRPC6 channels and contributes to their activation by diacylglycerol: essential role of podocin in formation of this complex." in: American journal of physiology. Cell physiology, Vol. 305, Issue 9, pp. C960-71, (2013) (PubMed).
: "Impaired Orai1-mediated resting Ca2+ entry reduces the cytosolic [Ca2+] and sarcoplasmic reticulum Ca2+ loading in quiescent junctophilin 1 knock-out myotubes." in: The Journal of biological chemistry, Vol. 285, Issue 50, pp. 39171-9, (2010) (PubMed).
: "Essential role of TRPC6 channels in G2/M phase transition and development of human glioma." in: Journal of the National Cancer Institute, Vol. 102, Issue 14, pp. 1052-68, (2010) (PubMed).
: "Evidence for STIM1- and Orai1-dependent store-operated calcium influx through ICRAC in vascular smooth muscle cells: role in proliferation and migration." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 8, pp. 2425-37, (2009) (PubMed).
Synonyms and alternative names related to TRPC6
transient receptor potential cation channel subfamily C member 6 (TRPC6), transient receptor potential cation channel, subfamily C, member 6 (Trpc6), transient receptor potential cation channel, subfamily C, member 6a (trpc6a), transient receptor potential cation channel subfamily C member 6 (Trpc6), transient receptor potential cation channel subfamily C member 6 (trpc6), AV025995, bZ1P14.9, FSGS2, LLHWJM002, LLHWJM003, LLHWJM004, mtrp6, si:rp71-1p14.9, TRP-6, TRP6, trp6, trpc6, Trrp6Protein level used designations for TRPC6
- TRP-6
- short transient receptor potential channel 6
- transient receptor protein 6
- calcium entry channel
- transient receptor potential cation channel, subfamily C, member 6
- transient receptor potential channel subfamily C member 6
- short transient receptor potential channel 6-like
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