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Troponin I Products

(Troponin I (TNNI))
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit\; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008].

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Featured Troponin I Categories

Troponin I Antibodies

High quality antibodies with extensive validation data.

Troponin I ELISA Kits

Reliable ELISA kits for a wide range of species.

Troponin I Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Troponin I Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN490086
Quantity 50 μg
Datasheet Datasheet
Reactivity Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (1)
Cat. No. ABIN746633
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IF (cc), IF (p)
Validations
  • (1)
Cat. No. ABIN746640
Quantity 100 μL
Datasheet Datasheet

Recommended Troponin I ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
Cat. No. ABIN6960197
Quantity 96 tests
Datasheet Datasheet
Reactivity Pig
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970872
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN4884913
Quantity 96 tests
Datasheet Datasheet

Recommended Troponin I Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN934731
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Human
Validations
  • (1)
Cat. No. ABIN935854
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN1543637
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Troponin I products

Lin, Schmidt, Fritz, Jeong, Cammarato, Foster, Biesiadecki, McKinsey, Woulfe: "Site-specific acetyl-mimetic modification of cardiac troponin I modulates myofilament relaxation and calcium sensitivity." in: Journal of molecular and cellular cardiology, Vol. 139, pp. 135-147, (2020) (PubMed).

Waas, Weerasekera, Kropp, Romero-Tejeda, Poon, Boheler, Burridge, Gundry: "Are These Cardiomyocytes? Protocol Development Reveals Impact of Sample Preparation on the Accuracy of Identifying Cardiomyocytes by Flow Cytometry." in: Stem cell reports, Vol. 12, Issue 2, pp. 395-410, (2020) (PubMed).

Apostolatos, Apostolatos, Ratnayake, Neuger, Sansil, Bourgeois, Acevedo-Duncan: "Preclinical testing of 5-amino-1-((1R,2S,3S,4R)-2,3-dihydroxy-4-methylcyclopentyl)-1H-imidazole-4-carboxamide: a potent protein kinase C-ι inhibitor as a potential prostate carcinoma therapeutic." in: Anti-cancer drugs, Vol. 30, Issue 1, pp. 65-71, (2019) (PubMed).

Woulfe, Ferrara, Pioner, Mahaffey, Coppini, Scellini, Ferrantini, Piroddi, Tesi, Poggesi, Jeong: "A Novel Method of Isolating Myofibrils From Primary Cardiomyocyte Culture Suitable for Myofibril Mechanical Study." in: Frontiers in cardiovascular medicine, Vol. 6, pp. 12, (2019) (PubMed).

Deng, Wang, Zhang, Xie, Cai, Li, Xie, Miao, Yang, Liu, Xia: "Propofol Through Upregulating Caveolin-3 Attenuates Post-Hypoxic Mitochondrial Damage and Cell Death in H9C2 Cardiomyocytes During Hyperglycemia." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 44, Issue 1, pp. 279-292, (2018) (PubMed).

Wang, Li, Wang, Mao, Yan, Wong, Xia, Irwin: "Repeated Non-Invasive Limb Ischemic Preconditioning Confers Cardioprotection Through PKC-Ԑ/STAT3 Signaling in Diabetic Rats." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 45, Issue 5, pp. 2107-2121, (2018) (PubMed).

Lin, Warren, Li, McKinsey, Russell: "Myofibril growth during cardiac hypertrophy is regulated through dual phosphorylation and acetylation of the actin capping protein CapZ." in: Cellular signalling, Vol. 28, Issue 8, pp. 1015-24, (2017) (PubMed).

Wang, Tan, Wang, Zhong: "Effect of levocarnitine on TIMP-1, ICAM-1 expression of rats with coronary heart disease and its myocardial protection effect." in: Asian Pacific journal of tropical medicine, Vol. 9, Issue 3, pp. 269-73, (2016) (PubMed).

Jin, Wang, Wang, Zhang, Yan, Hu: "Effects of acetaldehyde and L-carnitine on morphology and enzyme activity of myocardial mitochondria in rats." in: Molecular biology reports, Vol. 41, Issue 12, pp. 7923-8, (2015) (PubMed).

Zheng, Zhang, Yan, Chen, Qi, Zhang, Luo: "Protective effect of low dose gadolinium chloride against isoproterenol-induced myocardial injury in rat." in: Apoptosis : an international journal on programmed cell death, Vol. 20, Issue 9, pp. 1164-75, (2015) (PubMed).

Synonyms and alternative names related to Troponin I

wings up A (wupA), troponin I (tni), troponin I (LOC5574015), putative troponin I (Smp_059170.1), CG7178, Dmel\\CG7178, DmTpnI, DROTROPONI, HDP, hdp, hdp2, HL-I, HL08042, HLI, Tn I, TnI, tni, TpnI, wup-A, WupA

Protein level used designations for Troponin I

  • CG7178-PA
  • CG7178-PB
  • CG7178-PC
  • CG7178-PD
  • CG7178-PE
  • CG7178-PF
  • CG7178-PG
  • CG7178-PH
  • CG7178-PI
  • CG7178-PJ
  • CG7178-PK
  • CG7178-PL
  • CG7178-PM
  • haplo-lethal region I
  • held up
  • held-up
  • held-up2
  • heldup
  • troponin
  • troponin I
  • troponin-I
  • wings up
  • wings-up A
  • wupA-PA
  • wupA-PB
  • wupA-PC
  • wupA-PD
  • wupA-PE
  • wupA-PF
  • wupA-PG
  • wupA-PH
  • wupA-PI
  • wupA-PJ
  • wupA-PK
  • wupA-PL
  • wupA-PM
  • troponin i
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