TRKB Products
(Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))
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This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured TRKB Categories
TRKB Antibodies
High quality antibodies with extensive validation data.
TRKB ELISA Kits
Reliable ELISA kits for a wide range of species.
TRKB Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TRKB Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Rat
Application
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Validations
- (1)
- (5)
Cat. No.
ABIN725870
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (1)
- (5)
Cat. No.
ABIN6255997
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (4)
Cat. No.
ABIN6255941
Quantity
100 μL
Datasheet
Datasheet
Recommended TRKB ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6962433
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968902
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968901
Quantity
96 tests
Datasheet
Datasheet
Recommended TRKB Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275744
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124157
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Rat
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7197182
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our TRKB products
: "Adult trkB signaling in parvalbumin interneurons is essential to prefrontal network dynamics." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, (2021) (PubMed).: "Matrix metalloproteinase-9 increases the risk of cognitive impairment in schizophrenia." in: Nordic journal of psychiatry, Vol. 75, Issue 2, pp. 130-134, (2021) (PubMed).
: "Plasmalogen attenuates the development of hepatic steatosis and cognitive deficit through mechanism involving p75NTR inhibition." in: Redox biology, Vol. 43, pp. 102002, (2021) (PubMed).
: "The effects of rotenone on TH, BDNF and BDNF-related proteins in the brain and periphery: Relevance to early Parkinson's disease." in: Journal of chemical neuroanatomy, Vol. 97, pp. 23-32, (2019) (PubMed).
: "Effects and mechanisms of matrix metalloproteinase2 on neural differentiation of induced pluripotent stem cells." in: Brain research, Vol. 1678, pp. 407-418, (2018) (PubMed).
: "Differential Expression of miRNAs in the Hippocampi of Offspring Rats Exposed to Fluorine Combined with Aluminum during the Embryonic Stage and into Adulthood." in: Biological trace element research, (2018) (PubMed).
: "PirB Overexpression Exacerbates Neuronal Apoptosis by Inhibiting TrkB and mTOR Phosphorylation After Oxygen and Glucose Deprivation Injury." in: Cellular and molecular neurobiology, Vol. 37, Issue 4, pp. 707-715, (2017) (PubMed).
: "7,8-DHF Treatment Induces Cyr61 Expression to Suppress Hypoxia Induced ER Stress in HK-2 Cells." in: BioMed research international, Vol. 2016, pp. 5029797, (2017) (PubMed).
: "Brain-derived neurotrophic factor attenuates doxorubicin-induced cardiac dysfunction through activating Akt signalling in rats." in: Journal of cellular and molecular medicine, Vol. 21, Issue 4, pp. 685-696, (2017) (PubMed).
: "BDNF-mediates Down-regulation of MicroRNA-195 Inhibits Ischemic Cardiac Apoptosis in Rats." in: International journal of biological sciences, Vol. 12, Issue 8, pp. 979-89, (2017) (PubMed).
Synonyms and alternative names related to TRKB
neurotrophic receptor tyrosine kinase 2 (NTRK2), neurotrophic receptor tyrosine kinase 2 L homeolog (ntrk2.L), neurotrophic tyrosine kinase, receptor, type 2b (ntrk2b), neurotrophic receptor tyrosine kinase 2 S homeolog (ntrk2.S), neurotrophic receptor tyrosine kinase 2 (ntrk2), neurotrophic tyrosine kinase, receptor, type 2 (Ntrk2), neurotrophic receptor tyrosine kinase 2 (Ntrk2), AI848316, C030027L06Rik, gp145-trkb, GP145-TrkB, NTRK2, ntrk2, RATTRKB1, si:ch211-220b11.1, Tkrb, trk-B, Trk-B, trkb, TRKB, trkB, TrkB, trkb-b, TRKB1, trkB2, xtrkbProtein level used designations for TRKB
- neurotrophin receptor B xTrkB-alpha
- BDNF/NT-3 growth factors receptor
- neurotrophic tyrosine kinase, receptor, type 2
- BDNF/NT-3 growth factors receptor-like
- neurotrophic tyrosine kinase receptor type 2
- trk-B
- trkB tyrosine kinase
- tyrosine kinase receptor
- BDNF-tropomyosine receptor kinase B
- tropomyosin-related kinase B
- tyrosine kinase receptor B
- GP145-TrkB/GP95-TrkB
- neural receptor protein-tyrosine kinase (trkB)
- trkB protein
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