TRKA Products
(Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))
Categories
This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jul 2008].
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Featured TRKA Categories
TRKA Antibodies
High quality antibodies with extensive validation data.
TRKA ELISA Kits
Reliable ELISA kits for a wide range of species.
TRKA Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TRKA Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (1)
- (11)
Cat. No.
ABIN6256787
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro)
Validations
- (1)
- (5)
Cat. No.
ABIN726110
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
Cat. No.
ABIN7155192
Quantity
100 μg
Datasheet
Datasheet
Recommended TRKA ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968899
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968898
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN1720665
Quantity
96 tests
Datasheet
Datasheet
Recommended TRKA Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7092732
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7320045
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7320046
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our TRKA products
: "Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA." in: Cell reports, Vol. 26, Issue 13, pp. 3522-3536.e5, (2019) (PubMed).: "Oligo-Porphyran Ameliorates Neurobehavioral Deficits in Parkinsonian Mice by Regulating the PI3K/Akt/Bcl-2 Pathway." in: Marine drugs, Vol. 16, Issue 3, (2018) (PubMed).
: "Phenotypic and Functional Characterization of Peripheral Sensory Neurons derived from Human Embryonic Stem Cells." in: Scientific reports, Vol. 8, Issue 1, pp. 603, (2018) (PubMed).
: "Characterization of TRKA signaling in acute myeloid leukemia." in: Oncotarget, Vol. 9, Issue 53, pp. 30092-30105, (2018) (PubMed).
: "Cytoplasmic TrkA Expression as a Screen for Detecting NTRK1 Fusions in Colorectal Cancer." in: Translational oncology, Vol. 11, Issue 3, pp. 764-770, (2018) (PubMed).
: "OCD-like behavior is caused by dysfunction of thalamo-amygdala circuits and upregulated TrkB/ERK-MAPK signaling as a result of SPRED2 deficiency." in: Molecular psychiatry, (2017) (PubMed).
: "Nanoparticles increase human bronchial epithelial cell susceptibility to respiratory syncytial virus infection via nerve growth factor-induced autophagy." in: Physiological reports, Vol. 5, Issue 13, (2017) (PubMed).
: "Endophilin marks and controls a clathrin-independent endocytic pathway." in: Nature, Vol. 517, Issue 7535, pp. 460-5, (2015) (PubMed).
: "The interactions between nerve growth factor and gonadotrophins in bovine oviduct." in: Animal reproduction science, Vol. 149, Issue 3-4, pp. 117-23, (2014) (PubMed).
: "Humoral activity of cord blood-derived stem/progenitor cells: implications for stem cell-based adjuvant therapy of neurodegenerative disorders." in: PLoS ONE, Vol. 8, Issue 12, pp. e83833, (2014) (PubMed).
Synonyms and alternative names related to TRKA
neurotrophic receptor tyrosine kinase 1 (NTRK1), ret proto-oncogene (RET), neurotrophic receptor tyrosine kinase 1 (Ntrk1), neurotrophic tyrosine kinase, receptor, type 1 (Ntrk1), neurotrophic tyrosine kinase, receptor, type 1 (ntrk1), C80751, CDHF12, CDHR16, CTRKA, HSCR1, MEN2A, MEN2B, MTC, MTC1, p140-TrkA, PTC, RET-ELE1, RET51, Tkr, TRK, Trk, trk, Trk-A, TRK1, TRKA, TrkA, trka, trkAProtein level used designations for TRKA
- Oncogene TRK
- TRK1-transforming tyrosine kinase protein
- gp140trk
- high affinity nerve growth factor receptor
- tropomyosin-related kinase A
- tyrosine kinase receptor A
- RET transforming sequence
- cadherin family member 12
- cadherin-related family member 16
- hydroxyaryl-protein kinase
- proto-oncogene c-Ret
- proto-oncogene tyrosine-protein kinase receptor Ret
- receptor tyrosine kinase
- ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)
- TrkA neurotrophin receptor
- p140-TrkA
- slow nerve growth factor receptor
- trk
- trk-A
- trkA proto-oncogene receptor
- neurotrophic tyrosine kinase receptor type 1
- tropomyosin receptor kinase
- neurotrophic tyrosine kinase, receptor, type 1
- high affinity nerve growth factor receptor-like
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