TRIM30 Products
(Tripartite Motif Containing 30 (Trim30))
Categories
Trans-acting factor that regulates gene expression of interleukin 2 receptor alpha chain. May affect IL2R-alpha expression through cis-acting negative regulatory elements or through competition with proteins that bind to enhancer or activator sequences. Negatively regulates Toll-like receptor (TLR)-mediated activation of NFKB by promoting degradation of TAB2 and TAB3 and preventing TRAF6 autoubiquitination. Negatively regulates production of reactive oxygen species (ROS) which inhibits activation of the NLRP3 inflammasome complex. This, in turn, regulates activation of CASP1 and subsequent cleavage of IL1B and IL18. No activity detected against a range of retroviruses including a number of lentiviruses, gammaretroviruses and betaretroviruses.
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Featured TRIM30 Categories
TRIM30 Antibodies
High quality antibodies with extensive validation data.
Recommended TRIM30 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC
Validations
- (1)
Cat. No.
ABIN342695
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN342696
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, ELISA, IHC (p), IF
Validations
Cat. No.
ABIN6990956
Quantity
0.1 mg
Datasheet
Datasheet
Recommended TRIM30 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3133057
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our TRIM30 products
: "A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models." in: Nature communications, Vol. 8, Issue 1, pp. 1164, (2018) (PubMed).Synonyms and alternative names related to TRIM30
tripartite motif-containing 30 (Trim30), tripartite motif-containing 30A (Trim30a), RGD1563970, Rpt-1, Rpt1, Trim30Protein level used designations for TRIM30
- down regulatory protein of interleukin-2 receptor
- regulatory protein, T lymphocyte 1
- tripartite motif protein 30
- tripartite motif-containing 30
- tripartite motif-containing protein 30
- tripartite motif-containing protein 30A
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