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TRIM21 Products

(Tripartite Motif Containing 21 (TRIM21))

Categories

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008].

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Featured TRIM21 Categories

TRIM21 Antibodies

High quality antibodies with extensive validation data.

TRIM21 ELISA Kits

Reliable ELISA kits for a wide range of species.

TRIM21 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TRIM21 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, IF
Validations
  • (5)
Cat. No. ABIN6149506
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, FACS
Validations
  • (4)
Cat. No. ABIN184965
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IP, IF, ICC, IHC (p)
Validations
  • (4)
Cat. No. ABIN2856919
Quantity 100 μL
Datasheet Datasheet

Recommended TRIM21 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5564616
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1131346
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1131345
Quantity 96 tests
Datasheet Datasheet

Recommended TRIM21 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1323620
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323622
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2132321
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our TRIM21 products

Booth, Ramakrishnan, Narayan, Wollacott, Babcock, Shriver, Viswanathan: "Extending human IgG half-life using structure-guided design." in: mAbs, Vol. 10, Issue 7, pp. 1098-1110, (2019) (PubMed).

Ahn, Hwang, Zheng, Bang, Kim: "Enhancement of Th1/Th17 inflammation by TRIM21 in Behçet's disease." in: Scientific reports, Vol. 7, Issue 1, pp. 3018, (2017) (PubMed).

Manocha, Mishra, Sharma, Kumawat, Basu, Singh: "Regulatory role of TRIM21 in the type-I interferon pathway in Japanese encephalitis virus-infected human microglial cells." in: Journal of neuroinflammation, Vol. 11, pp. 24, (2014) (PubMed).

Chan, Di Donato, Hamel, Tseng, Buyon: "52-kD SS-A/Ro: genomic structure and identification of an alternatively spliced transcript encoding a novel leucine zipper-minus autoantigen expressed in fetal and adult heart." in: The Journal of experimental medicine, Vol. 182, Issue 4, pp. 983-92, (1995) (PubMed).

Synonyms and alternative names related to TRIM21

tripartite motif containing 21 (TRIM21), tripartite motif-containing 21 (Trim21), RNF81, RO52, Ro52, SSA, SSA1, Ssa1

Protein level used designations for TRIM21

  • tripartite motif-containing 21
  • 52 kDa Ro protein-like
  • tripartite motif containing 21
  • 52 kDa Ro protein
  • 52 kDa ribonucleoprotein autoantigen Ro/SS-A
  • E3 ubiquitin-protein ligase TRIM21
  • RING finger protein 81
  • SS-A
  • Sicca syndrome antigen A
  • Sjogren syndrome antigen A1 (52kDa, ribonucleoprotein autoantigen SS-A/Ro)
  • ro(SS-A)
  • sjoegren syndrome type A antigen
  • tripartite motif-containing protein 21
  • 52kD Ro/SSA autoantigen
  • Sjogren syndrome antigen A1
  • tripartite motif protein 21
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