TRIB3 Products
(Tribbles Homolog 3 (Drosophila) (TRIB3))
Categories
The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. [provided by RefSeq, Jul 2008].
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Featured TRIB3 Categories
TRIB3 Antibodies
High quality antibodies with extensive validation data.
TRIB3 ELISA Kits
Reliable ELISA kits for a wide range of species.
TRIB3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TRIB3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, RNAi
Validations
- (4)
Cat. No.
ABIN566162
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IP
Validations
- (4)
Cat. No.
ABIN566165
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN392789
Quantity
400 μL
Datasheet
Datasheet
Recommended TRIB3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970847
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6209171
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1163742
Quantity
96 tests
Datasheet
Datasheet
Recommended TRIB3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1323595
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1323593
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
- (1)
Cat. No.
ABIN7198334
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our TRIB3 products
: "Evaluation of Plasma TRB3 and Sestrin 2 Levels in Obese and Normal-Weight Children." in: Childhood obesity (Print), Vol. 13, Issue 5, pp. 409-414, (2018) (PubMed).: "Cellular stress induces TRB3/USP9x-dependent Notch activation in cancer." in: Oncogene, (2016) (PubMed).
: "Tribbles homolog 3 is induced by high glucose and associated with apoptosis in human endothelial cells." in: Molecular medicine reports, Vol. 12, Issue 2, pp. 1963-70, (2015) (PubMed).
: "High throughput kinase inhibitor screens reveal TRB3 and MAPK-ERK/TGFβ pathways as fundamental Notch regulators in breast cancer." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 5, pp. 1714-9, (2013) (PubMed).
: "Silence of TRIB3 suppresses atherosclerosis and stabilizes plaques in diabetic ApoE-/-/LDL receptor-/- mice." in: Diabetes, Vol. 61, Issue 2, pp. 463-73, (2012) (PubMed).
: "Tribbles homolog 3 denotes a poor prognosis in breast cancer and is involved in hypoxia response." in: Breast cancer research : BCR, Vol. 13, Issue 4, pp. R82, (2011) (PubMed).
: "Molecular basis for antagonism between PDGF and the TGFbeta family of signalling pathways by control of miR-24 expression." in: The EMBO journal, Vol. 29, Issue 3, pp. 559-73, (2010) (PubMed).
: "Genomic response of hypoxic Müller cells involves the very low density lipoprotein receptor as part of an angiogenic network." in: Experimental eye research, Vol. 88, Issue 5, pp. 928-37, (2009) (PubMed).
: "Abnormal expression of TRIB3 in colorectal cancer: a novel marker for prognosis." in: British journal of cancer, Vol. 101, Issue 10, pp. 1664-70, (2009) (PubMed).
: "SINK is a p65-interacting negative regulator of NF-kappaB-dependent transcription." in: The Journal of biological chemistry, Vol. 278, Issue 29, pp. 27072-9, (2003) (PubMed).
Synonyms and alternative names related to TRIB3
tribbles pseudokinase 3 (trib3), tribbles pseudokinase 3 (TRIB3), tribbles pseudokinase 3 (Trib3), C20orf97, Ifld2, NIPK, Nipk, SINK, SKIP3, TRB-3, TRB3, Trb3, TRIB3, zgc:76966Protein level used designations for TRIB3
- tribbles homolog 3
- tribbles homolog 3 (Drosophila)
- tribbles homolog 3-like
- TRB-3
- neuronal cell death inducible putative kinase
- neuronal cell death-inducible putative kinase
- p65-interacting inhibitor of NF-kappa-B
- p65-interacting inhibitor of NF-kappaB
- induced in fatty liver dystrophy 2
- Neuronal cell death Inducible Putative Kinase
- kinase
- tribbles 3
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