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TRF2 Products

(Telomeric Repeat Binding Factor 2 (TERF2))

Categories

This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic. [provided by RefSeq, Jul 2008].

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Featured TRF2 Categories

TRF2 Antibodies

High quality antibodies with extensive validation data.

TRF2 ELISA Kits

Reliable ELISA kits for a wide range of species.

TRF2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TRF2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
  • (5)
Cat. No. ABIN1724941
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7171733
Quantity 100 μg
Datasheet Datasheet
Reactivity Deer, Human, Mouse, Rat
Application WB, ELISA, IHC, IP, ICC, IHC (fro), FACS
Validations
  • (3)
Cat. No. ABIN208252
Quantity 0.1 mg
Datasheet Datasheet

Recommended TRF2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959883
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4973150
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1161144
Quantity 96 tests
Datasheet Datasheet

Recommended TRF2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322480
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7407409
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3095816
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TRF2 products

Galati, Magdinier, Colasanti, Bauwens, Pinte, Ricordy, Giraud-Panis, Pusch, Savino, Cacchione, Gilson: "TRF2 controls telomeric nucleosome organization in a cell cycle phase-dependent manner." in: PLoS ONE, Vol. 7, Issue 4, pp. e34386, (2012) (PubMed).

Conomos, Stutz, Hills, Neumann, Bryan, Reddel, Pickett: "Variant repeats are interspersed throughout the telomeres and recruit nuclear receptors in ALT cells." in: The Journal of cell biology, Vol. 199, Issue 6, pp. 893-906, (2012) (PubMed).

Diehl, Idowu, Kimmelshue, York, Jackson-Cook, Turner, Holt, Elmore: "Elevated TRF2 in advanced breast cancers with short telomeres." in: Breast cancer research and treatment, Vol. 127, Issue 3, pp. 623-30, (2011) (PubMed).

Huda, Tanaka, Mendonca, Gilley: "DNA damage-induced phosphorylation of TRF2 is required for the fast pathway of DNA double-strand break repair." in: Molecular and cellular biology, Vol. 29, Issue 13, pp. 3597-604, (2009) (PubMed).

Zhang, Zhang, Miao, Ding: "The telomeric protein TRF2 is critical for the protection of A549 cells from both telomere erosion and DNA double-strand breaks driven by salvicine." in: Molecular pharmacology, Vol. 73, Issue 3, pp. 824-32, (2008) (PubMed).

Muramatsu, Tahara, Ono, Tsuruo, Seimiya: "Telomere elongation by a mutant tankyrase 1 without TRF1 poly(ADP-ribosyl)ation." in: Experimental cell research, Vol. 314, Issue 5, pp. 1115-24, (2008) (PubMed).

Hockemeyer, Palm, Else, Daniels, Takai, Ye, Keegan, de Lange, Hammer: "Telomere protection by mammalian Pot1 requires interaction with Tpp1." in: Nature structural & molecular biology, Vol. 14, Issue 8, pp. 754-61, (2007) (PubMed).

van Overbeek, de Lange: "Apollo, an Artemis-related nuclease, interacts with TRF2 and protects human telomeres in S phase." in: Current biology : CB, Vol. 16, Issue 13, pp. 1295-302, (2006) (PubMed).

Biroccio, Rizzo, Elli, Koering, Belleville, Benassi, Leonetti, Stevens, DIncalci, Zupi, Gilson: "TRF2 inhibition triggers apoptosis and reduces tumourigenicity of human melanoma cells." in: European journal of cancer (Oxford, England : 1990), Vol. 42, Issue 12, pp. 1881-8, (2006) (PubMed).

Raz, Carlotti, Vermolen, van der Poel, Sloos, Knaän-Shanzer, de Vries, Hoeben, Young, Tanke, Garini, Dirks: "Changes in lamina structure are followed by spatial reorganization of heterochromatic regions in caspase-8-activated human mesenchymal stem cells." in: Journal of cell science, Vol. 119, Issue Pt 20, pp. 4247-56, (2006) (PubMed).

Synonyms and alternative names related to TRF2

telomeric repeat binding factor 2 (TERF2), telomeric repeat binding factor 2 (Terf2), telomeric repeat binding factor 2 L homeolog (terf2.L), TERF2, TRBF2, TRF2, trf2

Protein level used designations for TRF2

  • telomeric repeat binding factor 2
  • TTAGGG repeat-binding factor 2
  • telomeric DNA-binding protein
  • telomeric repeat binding protein 2
  • telomeric repeat-binding factor 2
  • TTAGGG-repeat binding factor 2 TRF2
  • telomeric repeat binding factor a
  • TTAGGG repeat binding factor 2
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