TRF1 Products
(Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))
Categories
This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products. [provided by RefSeq, Jul 2008].
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Featured TRF1 Categories
TRF1 Antibodies
High quality antibodies with extensive validation data.
TRF1 ELISA Kits
Reliable ELISA kits for a wide range of species.
TRF1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TRF1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ICC, IP
Validations
- (4)
Cat. No.
ABIN7438715
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (3)
Cat. No.
ABIN1683138
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7171728
Quantity
100 μL
Datasheet
Datasheet
Recommended TRF1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970579
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959882
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380509
Quantity
2 x 96 tests
Datasheet
Datasheet
Recommended TRF1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322476
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322478
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7403777
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our TRF1 products
: "Eroded human telomeres are more prone to remain uncapped and to trigger a G2 checkpoint response." in: Nucleic acids research, Vol. 41, Issue 2, pp. 900-11, (2013) (PubMed).: "Tethering telomeric double- and single-stranded DNA-binding proteins inhibits telomere elongation." in: The Journal of biological chemistry, Vol. 283, Issue 11, pp. 6935-41, (2008) (PubMed).
: "Telomere elongation by a mutant tankyrase 1 without TRF1 poly(ADP-ribosyl)ation." in: Experimental cell research, Vol. 314, Issue 5, pp. 1115-24, (2008) (PubMed).
: "Regulation of telomeric repeat binding factor 1 binding to telomeres by casein kinase 2-mediated phosphorylation." in: The Journal of biological chemistry, Vol. 283, Issue 20, pp. 14144-52, (2008) (PubMed).
: "Nucleostemin delays cellular senescence and negatively regulates TRF1 protein stability." in: Molecular and cellular biology, Vol. 26, Issue 24, pp. 9279-90, (2006) (PubMed).
: "The human telomeric protein TRF1 specifically recognizes nucleosomal binding sites and alters nucleosome structure." in: Journal of molecular biology, Vol. 360, Issue 2, pp. 377-85, (2006) (PubMed).
: "Closed chromatin loops at the ends of chromosomes." in: The Journal of cell biology, Vol. 166, Issue 2, pp. 161-5, (2004) (PubMed).
: "A signal peptide peptidase (SPP) reporter activity assay based on the cleavage of type II membrane protein substrates provides further evidence for an inverted orientation of the SPP active site ..." in: The Journal of biological chemistry, Vol. 279, Issue 41, pp. 43148-56, (2004) (PubMed).
: "A human telomeric protein." in: Science (New York, N.Y.), Vol. 270, Issue 5242, pp. 1663-7, (1996) (PubMed).
Synonyms and alternative names related to TRF1
telomeric repeat binding factor 1 (TERF1), telomeric repeat binding factor 1 (Terf1), telomeric repeat binding factor (NIMA-interacting) 1 (terf1), telomeric repeat binding factor 1 (Trf1), telomeric repeat binding factor (NIMA-interacting) 1 L homeolog (terf1.L), DKFZp459A0713, hTRF1-AS, PIN2, Pin2, t-TRF1, TERF1, terf1, TRBF1, Trbf1, TRF, TRF1, Trf1, trf1, wu:fb74c04Protein level used designations for TRF1
- NIMA-interacting protein 2
- TTAGGG repeat-binding factor 1
- telomeric protein Pin2/TRF1
- telomeric repeat-binding factor 1
- telomeric repeat binding factor 1
- telomeric repeat binding factor (NIMA-interacting) 1
- telomeric repeat-binding factor 1-like
- Telomeric repeat-binding factor 1
- telomeric repeat binding factor (NIMA-interacting) 1 L homeolog
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