TREX1 Products
(three Prime Repair Exonuclease 1 (TREX1))
Categories
This gene encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012].
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Featured TREX1 Categories
TREX1 Antibodies
High quality antibodies with extensive validation data.
TREX1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TREX1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
- (8)
Cat. No.
ABIN524703
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IP
Validations
- (3)
Cat. No.
ABIN7172071
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (3)
Cat. No.
ABIN6149486
Quantity
100 μL
Datasheet
Datasheet
Recommended TREX1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970621
Quantity
96 tests
Datasheet
Datasheet
Recommended TREX1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1323580
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1323578
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7419013
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our TREX1 products
: "Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells." in: Nature communications, Vol. 9, Issue 1, pp. 1249, (2018) (PubMed).: "DNase-active TREX1 frame-shift mutants induce serologic autoimmunity in mice." in: Journal of autoimmunity, Vol. 81, pp. 13-23, (2017) (PubMed).
: "Human three prime exonuclease TREX1 is induced by genotoxic stress and involved in protection of glioma and melanoma cells to anticancer drugs." in: Biochimica et biophysica acta, Vol. 1833, Issue 8, pp. 1832-43, (2013) (PubMed).
: "Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damage." in: Nucleic acids research, Vol. 38, Issue 19, pp. 6418-32, (2010) (PubMed).
: "A human DNA editing enzyme homologous to the Escherichia coli DnaQ/MutD protein." in: The EMBO journal, Vol. 18, Issue 13, pp. 3868-75, (1999) (PubMed).
: "Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3'-->5' exonucleases." in: The Journal of biological chemistry, Vol. 274, Issue 28, pp. 19655-60, (1999) (PubMed).
Synonyms and alternative names related to TREX1
three prime repair exonuclease 1 (CpipJ_CPIJ012074), three prime repair exonuclease 1 (Tsp_03749), three prime repair exonuclease 1 (TREX1), three prime repair exonuclease 1 (Trex1), 1661, AGS1, AU041952, CRV, DRN3, HERNS, RGD1309596Protein level used designations for TREX1
- three prime repair exonuclease 1
- 3' repair exonuclease 1
- 3'-5' exonuclease TREX1
- DNase III
- deoxyribonuclease III
- three prime exonuclease 1
- trophoblast expressed 1
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