TREM2 Products
(Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))
Categories
This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012].
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Featured TREM2 Categories
TREM2 Antibodies
High quality antibodies with extensive validation data.
TREM2 ELISA Kits
Reliable ELISA kits for a wide range of species.
TREM2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TREM2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7443632
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Pig, Rat
Application
WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (3)
- (4)
Cat. No.
ABIN749678
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC (p)
Validations
- (4)
Cat. No.
ABIN1539189
Quantity
400 μL
Datasheet
Datasheet
Recommended TREM2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6999586
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960173
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960174
Quantity
96 tests
Datasheet
Datasheet
Recommended TREM2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275789
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275790
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275786
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our TREM2 products
: "Metformin Therapy Attenuates Pro-inflammatory Microglia by Inhibiting NF-κB in Cuprizone Demyelinating Mouse Model of Multiple Sclerosis." in: Neurotoxicity research, (2021) (PubMed).: "Cerebrospinal Fluid Biomarkers in Cerebral Amyloid Angiopathy." in: Journal of Alzheimer's disease : JAD, Vol. 74, Issue 4, pp. 1189-1201, (2020) (PubMed).
: "Differential Roles of TREM2+ Microglia in Anterograde and Retrograde Axonal Injury Models." in: Frontiers in cellular neuroscience, Vol. 14, pp. 567404, (2020) (PubMed).
: "Increased TREM-2 expression on the subsets of CD11c+ cells in the lungs and lymph nodes during allergic airway inflammation." in: Scientific reports, Vol. 7, Issue 1, pp. 11853, (2019) (PubMed).
: "CSF sTREM2 in delirium-relation to Alzheimer's disease CSF biomarkers Aβ42, t-tau and p-tau." in: Journal of neuroinflammation, Vol. 15, Issue 1, pp. 304, (2019) (PubMed).
: "Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model." in: Nature communications, Vol. 10, Issue 1, pp. 1365, (2019) (PubMed).
: "Exercise as a potential modulator of inflammation in patients with Alzheimer's disease measured in cerebrospinal fluid and plasma." in: Experimental gerontology, Vol. 121, pp. 91-98, (2019) (PubMed).
: "Glial activation and inflammation along the Alzheimer's disease continuum." in: Journal of neuroinflammation, Vol. 16, Issue 1, pp. 46, (2019) (PubMed).
: "Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models." in: Neuron, Vol. 97, Issue 5, pp. 1032-1048.e5, (2019) (PubMed).
: "TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function." in: Neuron, Vol. 97, Issue 5, pp. 1023-1031.e7, (2019) (PubMed).
Synonyms and alternative names related to TREM2
triggering receptor expressed on myeloid cells 2 (TREM2), triggering receptor expressed on myeloid cells 2 (trem2), trem-like transcript 2 protein (LOC100228399), triggering receptor expressed on myeloid cells 2 (Trem2), trem-2, TREM-2, TREM-A1, TREM-B1, TREM2, trem2a, Trem2a, trem2b, Trem2b, trem2c, Trem2cProtein level used designations for TREM2
- triggering receptor expressed on myeloid cells 2
- triggering receptor expressed on monocytes 2
- triggering receptor expressed on myeloid cells 2a
- triggering receptor expressed on myeloid cells 2b
- triggering receptor expressed on myeloid cells 2c
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