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Transforming Growth Factor, beta 2 Proteins

(Transforming Growth Factor, beta 2 (TGFB2))
This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1\;7)(q41\;p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2010].
TGFB2 Protein (His tag) TGFB2 Protein (His tag) TGFB2 Protein (His tag) (ABIN1112028)

TGFB2 Origin: Human Host: Tobacco (Nicotiana benthamiana) Recombinant > 97 % by SDS-PAGE gel WB, Imm, ELISA, STD

TGFB2 Protein (AA 303-414) TGFB2 Protein (AA 303-414) TGFB2 Protein (AA 303-414) (ABIN7275710)

TGFB2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE

TGFB2 Protein (AA 303-414) (AVI tag,Biotin) TGFB2 Protein (AA 303-414) (AVI tag,Biotin) TGFB2 Protein (AA 303-414) (AVI tag,Biotin) (ABIN7275711)

TGFB2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE

Transforming Growth Factor, beta 2 Proteins by Origin

Find Transforming Growth Factor, beta 2 Proteins for a variety of species such as anti-Human Transforming Growth Factor, beta 2, anti-Mouse Transforming Growth Factor, beta 2, anti-Chicken Transforming Growth Factor, beta 2. The species listed below are among those available. Click on a link to go to the corresponding products.

Transforming Growth Factor, beta 2 Proteins by Source

Here you will find Transforming Growth Factor, beta 2 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Transforming Growth Factor, beta 2 Proteins by Protein Type

Here you can find Transforming Growth Factor, beta 2 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Transforming Growth Factor, beta 2 Proteins by Application

Find Transforming Growth Factor, beta 2 Proteins validated for a specific application such as WB, SDS, ELISA, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Transforming Growth Factor, beta 2 Proteins by Biological Activity

Find Transforming Growth Factor, beta 2 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular Transforming Growth Factor, beta 2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana benthamiana)
Validations
  • (4)
  • (2)
Cat. No. ABIN1112028
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275710
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275711
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1785602
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320669
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505179
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505540
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505428
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN6964328
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Human Cells
Validations
Cat. No. ABIN4371497
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Human Cells
Validations
Cat. No. ABIN7319106
Quantity 50 μg
Datasheet Datasheet
Reactivity Rhesus Monkey
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7389419
Quantity 100 μg
Datasheet Datasheet
Reactivity Rabbit
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7389416
Quantity 100 μg
Datasheet Datasheet
Reactivity Pig
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7389410
Quantity 100 μg
Datasheet Datasheet
Reactivity Goat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7389398
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Transforming Growth Factor, beta 2 Proteins

Zou, Sun: "An improved recombinant mammalian cell expression system for human transforming growth factor-beta2 and -beta3 preparations." in: Protein expression and purification, Vol. 50, Issue 1, pp. 9-17, (2006) (PubMed).

Massagué: "The transforming growth factor-beta family." in: Annual review of cell biology, Vol. 6, pp. 597-641, (1991) (PubMed).

Miller, Pelton, Derynck, Moses: "Transforming growth factor-beta. A family of growth regulatory peptides." in: Annals of the New York Academy of Sciences, Vol. 593, pp. 208-17, (1990) (PubMed).

Webb, Madisen, Rose, Purchio: "Structural and sequence analysis of TGF-beta 2 cDNA clones predicts two different precursor proteins produced by alternative mRNA splicing." in: DNA (Mary Ann Liebert, Inc.), Vol. 7, Issue 7, pp. 493-7, (1989) (PubMed).

ten Dijke, Hansen, Iwata, Pieler, Foulkes: "Identification of another member of the transforming growth factor type beta gene family." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 85, Issue 13, pp. 4715-9, (1988) (PubMed).

de Martin, Haendler, Hofer-Warbinek, Gaugitsch, Wrann, Schlüsener, Seifert, Bodmer, Fontana, Hofer: "Complementary DNA for human glioblastoma-derived T cell suppressor factor, a novel member of the transforming growth factor-beta gene family." in: The EMBO journal, Vol. 6, Issue 12, pp. 3673-7, (1988) (PubMed).

Madisen, Webb, Rose, Marquardt, Ikeda, Twardzik, Seyedin, Purchio: "Transforming growth factor-beta 2: cDNA cloning and sequence analysis." in: DNA (Mary Ann Liebert, Inc.), Vol. 7, Issue 1, pp. 1-8, (1988) (PubMed).

Aliases for Transforming Growth Factor, beta 2 Proteins

transforming growth factor beta 2 (TGFB2) Proteins
transforming growth factor beta 2 L homeolog (tgfb2.L) Proteins
transforming growth factor, beta 2 (Tgfb2) Proteins
transforming growth factor, beta receptor 2 (Tgfbr2) Proteins
transforming growth factor, beta 2 (tgfb2) Proteins
transforming growth factor beta 2 (Tgfb2) Proteins
BB105277 Proteins
LDS4 Proteins
MGF Proteins
TGF-B2 Proteins
TGF-beta2 Proteins
tgf-beta2 Proteins
Tgf-beta2 Proteins
TGF-beta 2 Proteins
Tgfb-2 Proteins
TGFB2 Proteins
tgfb2-A Proteins
TGFbeta2 Proteins
Tgfbr2T Proteins
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