Transforming Growth Factor, beta 2 Products
(Transforming Growth Factor, beta 2 (TGFB2))
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This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1\;7)(q41\;p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2010].
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Featured Transforming Growth Factor, beta 2 Categories
Transforming Growth Factor, beta 2 Antibodies
High quality antibodies with extensive validation data.
Transforming Growth Factor, beta 2 ELISA Kits
Reliable ELISA kits for a wide range of species.
Transforming Growth Factor, beta 2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Transforming Growth Factor, beta 2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, IF
Validations
- (6)
Cat. No.
ABIN3029221
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7429457
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7429460
Quantity
100 μL
Datasheet
Datasheet
Recommended Transforming Growth Factor, beta 2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6960089
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6960093
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960094
Quantity
96 tests
Datasheet
Datasheet
Recommended Transforming Growth Factor, beta 2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana benthamiana)
Validations
- (4)
- (2)
Cat. No.
ABIN1112028
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275710
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275711
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Transforming Growth Factor, beta 2 products
: "Crystallins Play a Crucial Role in Glaucoma and Promote Neuronal Cell Survival in an In Vitro Model Through Modulating Müller Cell Secretion." in: Investigative ophthalmology & visual science, Vol. 63, Issue 8, pp. 3, (2022) (PubMed).: "Angiocrine signals regulate quiescence and therapy resistance in bone metastasis." in: JCI insight, Vol. 4, Issue 13, (2020) (PubMed).
: "GFI1 downregulation promotes inflammation-linked metastasis of colorectal cancer." in: Cell death and differentiation, Vol. 24, Issue 5, pp. 929-943, (2018) (PubMed).
: "A microfluidic device for studying chemotaxis mechanism of bacterial cancer targeting." in: Scientific reports, Vol. 8, Issue 1, pp. 6394, (2018) (PubMed).
: "Plasminogen Activator Inhibitor-1 Protects Mice Against Cardiac Fibrosis by Inhibiting Urokinase-type Plasminogen Activator-mediated Plasminogen Activation." in: Scientific reports, Vol. 7, Issue 1, pp. 365, (2017) (PubMed).
: "Effects of ranibizumab on TGF-β1 and TGF-β2 production by human Tenon's fibroblasts: An in vitro study." in: Molecular vision, Vol. 21, pp. 1191-200, (2016) (PubMed).
: "SP600125 promotes resolution of allergic airway inflammation via TLR9 in an OVA-induced murine acute asthma model." in: Molecular immunology, (2015) (PubMed).
: "Influence of the Expression Level of O6-Alkylguanine-DNA Alkyltransferase on the Formation of DNA Interstrand Crosslinks Induced by Chloroethylnitrosoureas in Cells: A Quantitation Using ..." in: PLoS ONE, Vol. 10, Issue 3, pp. e0121225, (2015) (PubMed).
: "MicroRNA-26a modulates transforming growth factor beta-1-induced proliferation in human fetal lung fibroblasts." in: Biochemical and biophysical research communications, Vol. 454, Issue 4, pp. 512-517, (2014) (PubMed).
: "Elevated PLGF contributes to small-cell lung cancer brain metastasis." in: Oncogene, Vol. 32, Issue 24, pp. 2952-62, (2013) (PubMed).
Synonyms and alternative names related to Transforming Growth Factor, beta 2
transforming growth factor beta 2 (TGFB2), transforming growth factor beta 2 L homeolog (tgfb2.L), transforming growth factor, beta 2 (Tgfb2), transforming growth factor, beta receptor 2 (Tgfbr2), transforming growth factor, beta 2 (tgfb2), transforming growth factor beta 2 (Tgfb2), BB105277, LDS4, MGF, TGF-B2, TGF-beta2, tgf-beta2, Tgf-beta2, TGF-beta 2, Tgfb-2, TGFB2, tgfb2-A, TGFbeta2, Tgfbr2TProtein level used designations for Transforming Growth Factor, beta 2
- BSC-1 cell growth inhibitor
- G-TSF
- cetermin
- glioblastoma-derived T-cell suppressor factor
- polyergin
- transforming growth factor beta-2
- TGF-beta 2
- TGF-beta-2
- prepro-polypeptide
- Transforming growth factor beta-2
- transforming growth factor beta 2
- TGF-beta receptor type II
- TGF-beta receptor type-2
- TGF-beta type II receptor
- TGFR-2
- tbetaR-II
- transforming growth factor beta receptor type II
- transforming growth factor beta, receptor 2
- transforming growth factor, beta receptor 2
- transforming growth factor, beta receptor IIT
- transforming growth factor-b type II receptor
- transforming growth factor-beta receptor type II
- transforming growth factor-beta type II receptor
- tgf beta 2
- transforming growth factor, beta 2
- milk growth factor
- transforming growth factor-beta 2
- transforming growth factor beta-2-like
- TGF beta 2 protein
- transforming growth factor-beta2
- TGF beta 2
Did you look for something else?
- Transferrin Receptor 2
- Transferrin Receptor
- Transferrin
- Transcriptional Adaptor 3
- Transcription Termination Factor rho
- Transcription Factor MafK
- Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box)
- Transcription Factor 24
- Trans-Sialidase
- Tramadol
- TRAM2
- TRAM1L1
- TRAM1
- TRAK2
- TRAK1
- TraK
- TRAJ17
- TRAIP
- TRAIL
- TRAFs and NIK-Associated Protein
- Transgelin
- Transgelin 3
- Transglutaminase
- Transglutaminase 2
- Transglutaminase 5
- Transglutaminase 7
- Translation Initiation Factor 3 (INFC)
- Translin
- Translocase of Inner Mitochondrial Membrane 13 Homolog
- Transmembrane 7 Superfamily Member 4
- Transmembrane BAX Inhibitor Motif Containing 6
- Transmembrane Emp24 Protein Transport Domain Containing 1
- Transmembrane Protein 106B
- Transmembrane Protein 11
- Transmembrane Protein 131
- Transmembrane Protein 14C
- Transmembrane Protein 150B
- Transmembrane Protein 159
- Transmembrane Protein 18
- Transmembrane Protein 214
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