TRADD Products
(TNFRSF1A-Associated Via Death Domain (TRADD))
Categories
The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008].
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Featured TRADD Categories
TRADD Antibodies
High quality antibodies with extensive validation data.
TRADD ELISA Kits
Reliable ELISA kits for a wide range of species.
TRADD Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TRADD Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, IF, IP
Validations
- (5)
Cat. No.
ABIN7173904
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p)
Validations
- (1)
- (3)
Cat. No.
ABIN673314
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (4)
Cat. No.
ABIN6265701
Quantity
100 μL
Datasheet
Datasheet
Recommended TRADD ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1381565
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5690962
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6385690
Quantity
96 tests
Datasheet
Datasheet
Recommended TRADD Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1323491
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1323490
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7404962
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our TRADD products
: "Hydrogen sulfide protects against TNF-α induced neuronal cell apoptosis through miR-485-5p/TRADD signaling." in: Biochemical and biophysical research communications, Vol. 478, Issue 3, pp. 1304-9, (2016) (PubMed).: "Cytoplasmic TRADD confers a worse prognosis in glioblastoma." in: Neoplasia (New York, N.Y.), Vol. 15, Issue 8, pp. 888-97, (2013) (PubMed).
: "IL-6 cytoprotection in hyperoxic acute lung injury occurs via suppressor of cytokine signaling-1-induced apoptosis signal-regulating kinase-1 degradation." in: American journal of respiratory cell and molecular biology, Vol. 40, Issue 3, pp. 314-24, (2009) (PubMed).
: "Surface calreticulin mediates muramyl dipeptide-induced apoptosis in RK13 cells." in: The Journal of biological chemistry, Vol. 280, Issue 23, pp. 22425-36, (2005) (PubMed).
: "A20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1 complex in Jurkat T cells." in: Molecular and cellular biology, Vol. 22, Issue 17, pp. 6034-45, (2002) (PubMed).
: "Nuclear and cytoplasmic shuttling of TRADD induces apoptosis via different mechanisms." in: The Journal of cell biology, Vol. 157, Issue 6, pp. 975-84, (2002) (PubMed).
: "Transcriptional activation of TRADD mediates p53-independent radiation-induced apoptosis of glioma cells." in: Oncogene, Vol. 20, Issue 22, pp. 2826-35, (2001) (PubMed).
: "TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways." in: Cell, Vol. 84, Issue 2, pp. 299-308, (1996) (PubMed).
: "Systematic mutational analysis of the death domain of the tumor necrosis factor receptor 1-associated protein TRADD." in: The Journal of biological chemistry, Vol. 271, Issue 16, pp. 9858-62, (1996) (PubMed).
: "The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation." in: Cell, Vol. 81, Issue 4, pp. 495-504, (1995) (PubMed).
Synonyms and alternative names related to TRADD
TNFRSF1A associated via death domain (TRADD), conjugal transfer protein D (traDd), TNFRSF1A-associated via death domain (Tradd), TNFRSF1A-associated via death domain L homeolog (tradd.L), tnfrsf1a-associated via death domain (tradd), TNFRSF1A associated via death domain (tradd), 9130005N23Rik, AA930854, Hs.89862, TRADD, tradd, wu:fc59e02, zgc:103556Protein level used designations for TRADD
- TNFRSF1A-associated via death domain
- conjugal transfer protein D
- TNFR1-associated death domain protein
- tumor necrosis factor receptor type 1 associated death domain protein
- tumor necrosis factor receptor type 1-associated DEATH domain protein
- tumor necrosis factor receptor-1-associated protein
- TNF receptor 1 associated signal transducer
- TNFR1-associated DEATH domain protein
- Tumor necrosis factor receptor type 1-associated DEATH domain protein
- TNFRSF1A-associated via death domain protein
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