TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) Products
(TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))
Categories
Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation and protects the phosphorylated residue against dephosphorylation (By similarity).
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Featured TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) Categories
TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) Antibodies
High quality antibodies with extensive validation data.
TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) ELISA Kits
Reliable ELISA kits for a wide range of species.
TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN6261299
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IP, IHC (p), ICC
Validations
- (3)
Cat. No.
ABIN5711936
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP, ICC, FACS, DB
Validations
- (3)
Cat. No.
ABIN931062
Quantity
100 μg
Datasheet
Datasheet
Recommended TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1160841
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1160842
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Validations
Cat. No.
ABIN1160840
Quantity
96 tests
Datasheet
Datasheet
Recommended TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125423
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1323477
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN2734107
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) products
: "Adducin-1 is essential for spindle pole integrity through its interaction with TPX2." in: EMBO reports, Vol. 19, Issue 8, (2019) (PubMed).: "TPX2/Aurora kinase A signaling as a potential therapeutic target in genomically unstable cancer cells." in: Oncogene, Vol. 38, Issue 6, pp. 852-867, (2019) (PubMed).
: "P190RhoGAP prevents mitotic spindle fragmentation and is required to activate Aurora A kinase at acentriolar poles." in: Chromosoma, Vol. 127, Issue 3, pp. 375-386, (2019) (PubMed).
: "HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development." in: eLife, Vol. 6, (2018) (PubMed).
: "USP35 regulates mitotic progression by modulating the stability of Aurora B." in: Nature communications, Vol. 9, Issue 1, pp. 688, (2018) (PubMed).
: "Distribution of Eg5 and TPX2 in mitosis: Insight from CRISPR tagged cells." in: Cytoskeleton (Hoboken, N.J.), Vol. 75, Issue 12, pp. 508-521, (2018) (PubMed).
: "FSH Regulates mRNA Translation in Mouse Oocytes and Promotes Developmental Competence." in: Endocrinology, Vol. 157, Issue 2, pp. 872-82, (2016) (PubMed).
: "The Clathrin-dependent Spindle Proteome." in: Molecular & cellular proteomics : MCP, Vol. 15, Issue 8, pp. 2537-53, (2016) (PubMed).
: "Regulation of Kif15 localization and motility by the C-terminus of TPX2 and microtubule dynamics." in: Molecular biology of the cell, Vol. 28, Issue 1, pp. 65-75, (2016) (PubMed).
: "Phosphorylation of targeting protein for Xenopus kinesin-like protein 2 (TPX2) at threonine 72 in spindle assembly." in: The Journal of biological chemistry, Vol. 290, Issue 14, pp. 9122-34, (2015) (PubMed).
Synonyms and alternative names related to TPX2, Microtubule-Associated, Homolog (Xenopus Laevis)
TPX2, microtubule nucleation factor (TPX2), TPX2, microtubule-associated (Tpx2), TPX2, microtubule nucleation factor (Tpx2), TPX2, microtubule-associated, homolog (Xenopus laevis) (TPX2), TPX2, microtubule-associated S homeolog (tpx2.S), TPX2, microtubule-associated L homeolog (tpx2.L), 2610005B21Rik, C20orf1, C20orf2, DIL-2, dil-2, DIL2, dil2, FLS353, GD:C20orf1, HCA519, HCTP4, hctp4, p100, REPP86, repp86, TPX2, tpx2Protein level used designations for TPX2, Microtubule-Associated, Homolog (Xenopus Laevis)
- TPX2, microtubule-associated protein homolog
- TPX2, microtubule-associated, homolog
- differentially expressed in cancerous and non-cancerous lung cells 2
- differentially expressed in lung cells
- hepatocellular carcinoma-associated antigen 519
- preferentially expressed in colorectal cancer
- protein fls353
- restricted expression proliferation associated protein 100
- restricted expression proliferation-associated protein 100
- targeting protein for Xklp2
- TPX2, microtubule-associated, homolog (Xenopus laevis)
- targeting protein for Xklp2-like
- TPX2 protein, microtubule-associated
- targeting protein for Xklp2-B
- targeting protein for Xklp2-A
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