TPP1 Products
(Tripeptidyl Peptidase I (TPP1))
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This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq, Jul 2008].
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Featured TPP1 Categories
TPP1 Antibodies
High quality antibodies with extensive validation data.
TPP1 ELISA Kits
Reliable ELISA kits for a wide range of species.
TPP1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TPP1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7435157
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7440935
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (1)
- (4)
Cat. No.
ABIN560411
Quantity
100 μg
Datasheet
Datasheet
Recommended TPP1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970869
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960181
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6960182
Quantity
96 tests
Datasheet
Datasheet
Recommended TPP1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1323447
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1323446
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Human Cells
Validations
Cat. No.
ABIN4370873
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our TPP1 products
: "Role of TMPRSS4 Modulation in Breast Cancer Cell Proliferation." in: Asian Pacific journal of cancer prevention : APJCP, Vol. 20, Issue 6, pp. 1849-1856, (2019) (PubMed).: "Pharmacological Effects on Ceroid Lipofuscin and Neuronal Structure in Cln3∆ex7/8Mouse Brain Cultures." in: Journal of molecular neuroscience : MN, Vol. 63, Issue 1, pp. 100-114, (2017) (PubMed).
: "Altered expression of TPP1 in fibroblast-like synovial cells might be involved in the pathogenesis of rheumatoid arthritis." in: Rheumatology international, Vol. 32, Issue 8, pp. 2503-10, (2012) (PubMed).
: "Mutations in CLN7/MFSD8 are a common cause of variant late-infantile neuronal ceroid lipofuscinosis." in: Brain : a journal of neurology, Vol. 132, Issue Pt 3, pp. 810-9, (2009) (PubMed).
Synonyms and alternative names related to TPP1
tripeptidyl peptidase I (tpp1), tripeptidyl-peptidase 1 (NAEGRDRAFT_78259), tripeptidyl-peptidase 1 (MCYG_00184), tripeptidyl-peptidase 1 (MGYG_05881), tripeptidyl-peptidase 1 (MGYG_00757), tripeptidyl peptidase 1 (tpp1), tripeptidyl peptidase 1 (TPP1), tripeptidyl peptidase 1 (Tpp1), tripeptidyl peptidase I (Tpp1), cln2, CLN2, Cln2, fa01b09, im:7149243, LPIC, TPP-1, TPP-I, wu:fa01b09Protein level used designations for TPP1
- ceroid-lipofuscinosis, neuronal 2
- tripeptidyl-peptidase 1
- cell growth-inhibiting gene 1 protein
- growth-inhibiting protein 1
- lysosomal pepstatin insensitive protease
- tripeptidyl aminopeptidase
- LPIC
- TPP-1
- TPP-I
- lysosomal pepstatin-insensitive protease
- tripeptidyl peptidase 1
- tripeptidyl-peptidase I
- tripeptidyl peptidase-I
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