TPM3 Products
(Tropomyosin 3 (TPM3))
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This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured TPM3 Categories
TPM3 Antibodies
High quality antibodies with extensive validation data.
TPM3 ELISA Kits
Reliable ELISA kits for a wide range of species.
TPM3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TPM3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (5)
Cat. No.
ABIN3021721
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (4)
Cat. No.
ABIN563236
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (1)
- (3)
Cat. No.
ABIN521063
Quantity
100 μg
Datasheet
Datasheet
Recommended TPM3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960184
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960185
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5659550
Quantity
96 tests
Datasheet
Datasheet
Recommended TPM3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1323437
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125505
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN667651
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our TPM3 products
: "Hypoxic regulation of RIOK3 is a major mechanism for cancer cell invasion and metastasis." in: Oncogene, (2014) (PubMed).: "The QKI-6 RNA binding protein regulates actin-interacting protein-1 mRNA stability during oligodendrocyte differentiation." in: Molecular biology of the cell, Vol. 21, Issue 17, pp. 3029-40, (2010) (PubMed).
: "An economic evaluation of atorvastatin for primary prevention of cardiovascular events in type 2 diabetes." in: PharmacoEconomics, Vol. 26, Issue 4, pp. 329-39, (2008) (PubMed).
: "Characterisation of two antibodies to oligomeric Abeta and their use in ELISAs on human brain tissue homogenates." in: Journal of neuroscience methods, Vol. 176, Issue 2, pp. 206-12, (2008) (PubMed).
Synonyms and alternative names related to TPM3
tropomyosin 3 (TPM3), tropomyosin 3 (tpm3), tropomyosin 3, gamma (Tpm3), tropomyosin 3 (Tpm3), tropomyosin 3 S homeolog (tpm3.S), CAPM1, cb674, CFTD, fa17b11, fb83b01, fk41e01, gamma-TM, hm:zeh0298, hscp30, hTM30nm, hTMnm, NEM1, OK/SW-cl.5, TM-5, TM3, tm3, TM5, Tm5NM, TM30, TM30nm, Tpm-5, TPM3, tpm3, tpm3.L, Tpm5, TPMsk3, TRK, Trop-5, wu:fa17b11, wu:fb83b01, wu:fk41e01, zeh0298, zgc:77592Protein level used designations for TPM3
- alpha-tropomyosin, slow skeletal
- cytoskeletal tropomyosin TM30
- heat-stable cytoskeletal protein 30 kDa
- tropomyosin alpha-3 chain
- tropomyosin gamma
- tropomyosin-5
- gamma-tropomyosin
- tropomyosin-3
- tropomyosin 3
- skalphaTM.2
- tropomyosin 5
- nonmuscle tropomyosin 5
- tropomyosin 3, gamma
- tropomyosin non-muscle
- tropomyosin 3 L homeolog
- tropomyosin 3 S homeolog
- min alpha-trop
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