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TP53BP1 Products

(Tumor Protein P53 Binding Protein 1 (TP53BP1))
May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation. Binds to sites of DNA damage. Plays a role in the response to DNA damage (By similarity).

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Featured TP53BP1 Categories

TP53BP1 Antibodies

High quality antibodies with extensive validation data.

TP53BP1 ELISA Kits

Reliable ELISA kits for a wide range of species.

TP53BP1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TP53BP1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, ELISA, FACS
Validations
  • (2)
  • (6)
Cat. No. ABIN1724820
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, ICC, IHC (p), IHC (fro)
Validations
  • (4)
Cat. No. ABIN2855433
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ICC, IHC (p)
Validations
  • (5)
Cat. No. ABIN3044038
Quantity 100 μg
Datasheet Datasheet

Recommended TP53BP1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971005
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960308
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380332
Quantity 2 x 96 tests
Datasheet Datasheet

Recommended TP53BP1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323384
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7408840
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2734078
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our TP53BP1 products

Parisotto, Grelet, El Bizri, Dai, Terzic, Eckert, Gargowitsch, Bornert, Metzger: "PTEN deletion in luminal cells of mature prostate induces replication stress and senescence in vivo." in: The Journal of experimental medicine, Vol. 215, Issue 6, pp. 1749-1763, (2019) (PubMed).

Benkafadar, François, Affortit, Casas, Ceccato, Menardo, Venail, Malfroy-Camine, Puel, Wang: "ROS-Induced Activation of DNA Damage Responses Drives Senescence-Like State in Postmitotic Cochlear Cells: Implication for Hearing Preservation." in: Molecular neurobiology, (2019) (PubMed).

Tumini, Herrera-Moyano, San Martín-Alonso, Barroso, Galmarini, Aguilera: "The Antitumor Drugs Trabectedin and Lurbinectedin Induce Transcription-Dependent Replication Stress and Genome Instability." in: Molecular cancer research : MCR, Vol. 17, Issue 3, pp. 773-782, (2019) (PubMed).

Muñoz-Galván, Lucena-Cacace, Perez, Otero-Albiol, Gomez-Cambronero, Carnero: "Tumor cell-secreted PLD increases tumor stemness by senescence-mediated communication with microenvironment." in: Oncogene, Vol. 38, Issue 8, pp. 1309-1323, (2019) (PubMed).

Fernandez-Vidal, Arnaud, Maumus, Chevalier, Mirey, Salles, Vignard, Boutet-Robinet: "Exposure to the Fungicide Captan Induces DNA Base Alterations and Replicative Stress in Mammalian Cells." in: Environmental and molecular mutagenesis, Vol. 60, Issue 3, pp. 286-297, (2019) (PubMed).

Köcher, Beyer, Lange, Nordquist, Volquardsen, Burdak-Rothkamm, Schlomm, Petersen, Rothkamm, Mansour: "A functional ex vivo assay to detect PARP1-EJ repair and radiosensitization by PARP-inhibitor in prostate cancer." in: International journal of cancer, Vol. 144, Issue 7, pp. 1685-1696, (2019) (PubMed).

Becker, Cuella-Martin, Barazas, Liu, Oliveira, Oliver, Bilham, Holt, Blackford, Heierhorst, Jonkers, Rottenberg, Chapman: "The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity." in: Nature communications, Vol. 9, Issue 1, pp. 5406, (2019) (PubMed).

Bodo, Campagne, Thin, Higginson, Vargas, Hua, Fuller, Ackerstaff, Russell, Zhang, Klingler, Cho, Kaag, Mazaheri, Rimner, Manova-Todorova, Epel, Zatcky, Cleary, Rao, Yamada, Zelefsky, Halpern et al.: "Single-dose radiotherapy disables tumor cell homologous recombination via ischemia/reperfusion injury. ..." in: The Journal of clinical investigation, Vol. 129, Issue 2, pp. 786-801, (2019) (PubMed).

Boscolo Sesillo, Fox, Sacco: "Muscle Stem Cells Give Rise to Rhabdomyosarcomas in a Severe Mouse Model of Duchenne Muscular Dystrophy." in: Cell reports, Vol. 26, Issue 3, pp. 689-701.e6, (2019) (PubMed).

Lafarga, Sung, Haneke, Roessig, Pauleau, Bruer, Rodriguez-Acebes, Lopez-Contreras, Gruss, Erhardt, Mendez, Fernandez-Capetillo, Stoecklin: "TIAR marks nuclear G2/M transition granules and restricts CDK1 activity under replication stress." in: EMBO reports, Vol. 20, Issue 1, (2019) (PubMed).

Synonyms and alternative names related to TP53BP1

tumor protein p53 binding protein 1 (TP53BP1), tumor protein p53 binding protein 1 (tp53bp1), tumor suppressor p53-binding protein 1 (LOC100550605), tumor protein p53 binding protein 1 (predicted), 5 prime (TP53BP1), transformation related protein 53 binding protein 1 (Trp53bp1), tumor protein p53 binding protein 1 (Tp53bp1), 53BP1, m53BP1, MGC160112, p202, TP53BP1, Tp53bp1, Trp53bp1

Protein level used designations for TP53BP1

  • tumor protein p53 binding protein 1
  • tumor protein p53 binding protein, 1
  • tumor suppressor p53-binding protein 1-like
  • tumor protein p53 binding protein 1 (predicted), 5 prime
  • tumor protein p53 binding protein 1 (predicted), 3 prime
  • murine p53-binding protein
  • p53-binding protein 1
  • p53BP1
  • transformation related protein 53 binding-protein 1
  • tumor suppressor p53-binding protein 1
  • tumor protein 53-binding protein, 1
  • tumor protein p53-binding protein, 1
  • transformation related protein 53 binding protein 1
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