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Topoisomerase II alpha Proteins

(Topoisomerase (DNA) II alpha 170kDa (TOP2A))

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromosome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia. [provided by RefSeq, Jul 2010].

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Topoisomerase II alpha Protein (AA 1435-1531) (GST tag) (ABIN1323347)

TOP2A Origin: Human Host: Wheat germ Recombinant WB, AP, AA, ELISA

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custom-made TOP2A Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris Page, Western Blot WB, SDS

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custom-made TOP2A Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris Page, Western Blot WB, SDS

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Topoisomerase II alpha Proteins by Grade

Find Topoisomerase II alpha Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

Topoisomerase II alpha Proteins by Origin

Find Topoisomerase II alpha Proteins for a variety of species such as anti-Human Topoisomerase II alpha, anti-Mouse Topoisomerase II alpha, anti-Rat Topoisomerase II alpha. The species listed below are among those available. Click on a link to go to the corresponding products.

Topoisomerase II alpha Proteins by Source

Here you will find Topoisomerase II alpha Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Topoisomerase II alpha Proteins by Protein Type

Here you can find Topoisomerase II alpha Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Topoisomerase II alpha Proteins by Application

Find Topoisomerase II alpha Proteins validated for a specific application such as WB, SDS, AP, AA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Topoisomerase II alpha Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

Topoisomerase II alpha Protein (AA 1435-1531) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1323347

Quantity 10 μg

Datasheet Datasheet

Topoisomerase II alpha Protein (AA 1-1528) (His tag)

Reactivity Mouse

Source HEK-293 Cells

Validations

Cat. No. ABIN7563577

Quantity 1 mg

Datasheet Datasheet

Topoisomerase II alpha Protein (AA 1-1531) (His tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7555788

Quantity 1 mg

Datasheet Datasheet

Topoisomerase II alpha Protein (AA 1354-1473)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7013599

Quantity 100 μg

Datasheet Datasheet

Topoisomerase II alpha Protein

Reactivity Human, Mouse, Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN2751809

Quantity 5 applications

Datasheet Datasheet

Aliases for Topoisomerase II alpha Proteins

DNA topoisomerase II alpha (TOP2A) Proteins
DNA topoisomerase II, alpha isozyme (Bm1_08705) Proteins
topoisomerase (DNA) II alpha (Top2a) Proteins
DNA topoisomerase II alpha (Top2a) Proteins
topoisomerase (DNA) II alpha (TOP2A) Proteins
Zincin-like metalloproteases family protein (AT5G10540) Proteins
DNA topoisomerase II alpha (top2a) Proteins
F12B17.110 Proteins
F12B17_110 Proteins
fc08c07 Proteins
thimet metalloendopeptidase 2 Proteins
Top-2 Proteins
TOP-2 Proteins
TOP2 Proteins
TOP2A Proteins
TP2A Proteins
wu:fc08c07 Proteins

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Topoisomerase II alpha Proteins by Grade

Topoisomerase II alpha Proteins by Origin

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Topoisomerase II alpha Proteins by Application

Popular Topoisomerase II alpha Proteins

Aliases for Topoisomerase II alpha Proteins

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