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TOP2B Proteins

(Topoisomerase (DNA) II beta 180kDa (TOP2B))

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, beta, is localized to chromosome 3 and the alpha form is localized to chromosome 17. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia. Alternative splicing of this gene results in two transcript variants\; however, the second variant has not yet been fully described. [provided by RefSeq, Jul 2008].

recommended

TOP2B Protein (AA 1411-1523) (GST tag) (ABIN1323349)

TOP2B Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

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recommended

TOP2B Protein (AA 458-667) (His tag) (ABIN7397666)

TOP2B Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS, Imm, PC

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recommended

TOP2B Protein (AA 446-655) (His tag) (ABIN7406401)

TOP2B Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC

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TOP2B Proteins by Origin

Find TOP2B Proteins for a variety of species such as anti-Human TOP2B, anti-Mouse TOP2B. The species listed below are among those available. Click on a link to go to the corresponding products.

TOP2B Proteins by Source

Here you will find TOP2B Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

TOP2B Proteins by Protein Type

Here you can find TOP2B Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

TOP2B Proteins by Application

Find TOP2B Proteins validated for a specific application such as WB, SDS, ELISA, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular TOP2B Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

TOP2B Protein (AA 1411-1523) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1323349

Quantity 10 μg

Datasheet Datasheet

TOP2B Protein (AA 458-667) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7397666

Quantity 100 μg

Datasheet Datasheet

TOP2B Protein (AA 446-655) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7406401

Quantity 100 μg

Datasheet Datasheet

TOP2B Protein

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN3011939

Quantity 100 μg

Datasheet Datasheet

TOP2B Protein

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN6126495

Quantity 100 μg

Datasheet Datasheet

Aliases for TOP2B Proteins

DNA topoisomerase II beta (TOP2B) Proteins
topoisomerase (DNA) II beta (Top2b) Proteins
DNA topoisomerase II beta (Top2b) Proteins
microRNA 4442 (MIR4442) Proteins
D230016L12Rik Proteins
Top-2 Proteins
TOP2B Proteins
top2beta Proteins
TOPIIB Proteins

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TOP2B Proteins by Origin

TOP2B Proteins by Source

TOP2B Proteins by Protein Type

TOP2B Proteins by Application

Popular TOP2B Proteins

Aliases for TOP2B Proteins

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