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TOP2 Products

(DNA Topoisomerase II (TOP2))
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.

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Featured TOP2 Categories

TOP2 Antibodies

High quality antibodies with extensive validation data.

TOP2 ELISA Kits

Reliable ELISA kits for a wide range of species.

TOP2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TOP2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, ICC
Validations
  • (3)
Cat. No. ABIN1860829
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, ICC
Validations
  • (3)
Cat. No. ABIN1860828
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, ICC
Validations
  • (2)
Cat. No. ABIN1860830
Quantity 100 μL
Datasheet Datasheet

Recommended TOP2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6955424
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6955426
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955425
Quantity 96 tests
Datasheet Datasheet

Recommended TOP2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7406050
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7392089
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7411309
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our TOP2 products

Verma, Fatima, Dudi, Tabassum, Iqbal, Kumar, Luqman, Mondhe, Chanda, Khan, Shanker, Negi: "Antiproliferative activity of diarylnaphthylpyrrolidine derivative via dual target inhibition." in: European journal of medicinal chemistry, Vol. 188, pp. 111986, (2020) (PubMed).

Kumar, Ravi, Verma, Fatima, Hasanain, Singh, Sarkar, Luqman, Chanda, Negi: "Synthesis of pharmacologically important naphthoquinones and anticancer activity of 2-benzyllawsone through DNA topoisomerase-II inhibition." in: Bioorganic & medicinal chemistry, Vol. 25, Issue 4, pp. 1364-1373, (2017) (PubMed).

Xu, Chen, Wang, Xu, Yuan, Li, Bai, Xue: "Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase I and topoisomerase II." in: Journal of experimental & clinical cancer research : CR, Vol. 35, Issue 1, pp. 178, (2016) (PubMed).

Xie, Lam: "Characterization of a DNA Topoisomerase II cDNA from Arabidopsis thaliana." in: Plant physiology, Vol. 106, Issue 4, pp. 1701-2, (1995) (PubMed).

Synonyms and alternative names related to TOP2

topoisomerase II (TOP2), DNA topoisomerase II (A583L), DNA topoisomerase II (top2), DNA topoisomerase II (CNA03600), DNA topoisomerase 2 (TOP2), DNA topoisomerase II (Tb09.160.4090), DNA topoisomerase II (Tb11.01.3390), DNA topoisomerase II (TOP2), DNA topoisomerase ii (LMJF_28_2280), type IIA topoisomerase; DNA gyrase topoisomerase IV B subunit (top2), Topoisomerase 2 (Top2), CG10223, CHRAC, dCHRAC, DDBDRAFT_0191045, DDBDRAFT_0231510, DDB_0191045, DDB_0231510, Dmel\\CG10223, dTopoII, ptr11, TOP2, top2, TopII, Topoii, TOPO II, TOPOII, Topo II, TopoII, topo II, topoII

Protein level used designations for TOP2

  • DNA topoisomerase 2
  • DNA topoisomerase II
  • DNA topoisomerase ii
  • CG10223-PA
  • CG10223-PB
  • Top2-PA
  • Top2-PB
  • topoisomerase 2
  • topoisomerase II
  • type II DNA topoisomerase
  • type II topoisomerase
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