TNPO2 Products
(Transportin 2 (TNPO2))
Categories
Probably functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity).
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Featured TNPO2 Categories
TNPO2 Antibodies
High quality antibodies with extensive validation data.
TNPO2 ELISA Kits
Reliable ELISA kits for a wide range of species.
TNPO2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TNPO2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN565456
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6739029
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6739028
Quantity
100 μL
Datasheet
Datasheet
Recommended TNPO2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970835
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960152
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5659510
Quantity
96 tests
Datasheet
Datasheet
Recommended TNPO2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1323300
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7397279
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3136955
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our TNPO2 products
: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).Synonyms and alternative names related to TNPO2
transportin 2 (TNPO2), transportin 2 L homeolog (tnpo2.L), transportin 2 (Tnpo2), transportin 2 (importin 3, karyopherin beta 2b) (tnpo2), transportin 2 (importin 3, karyopherin beta 2b) (Tnpo2), 1110034O24Rik, AA414969, AI464345, AI852433, ik:tdsubc_2a7, IPO3, Knpb2b, KPNB2B, Kpnb2b, tdsubc_2a7, TNPO2, TRN2, wu:fb01c02, wu:fe01f03, wu:fe16e12, xx:tdsubc_2a7, zgc:101009Protein level used designations for TNPO2
- transportin 2
- transportin 2 (importin 3, karyopherin beta 2b)
- importin 3
- karyopherin beta 2b, transportin
- karyopherin beta-2b
- transportin-2
- fb01c02
- fe01f03
- karyopherin (importin) beta 2b
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