TNNI1 Products
(Slow Skeletal Troponin I (TNNI1))
Categories
Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit\; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes. [provided by RefSeq, Jul 2008].
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Featured TNNI1 Categories
TNNI1 Antibodies
High quality antibodies with extensive validation data.
TNNI1 ELISA Kits
Reliable ELISA kits for a wide range of species.
TNNI1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TNNI1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7435427
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB, IHC
Validations
- (1)
- (4)
Cat. No.
ABIN2777151
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7435424
Quantity
100 μL
Datasheet
Datasheet
Recommended TNNI1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6960188
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970874
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962286
Quantity
96 tests
Datasheet
Datasheet
Recommended TNNI1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125117
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1323277
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2132239
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our TNNI1 products
: "Dietary leucine supplementation alters energy metabolism and induces slow-to-fast transitions in longissimus dorsi muscle of weanling piglets." in: The British journal of nutrition, Vol. 117, Issue 9, pp. 1222-1234, (2017) (PubMed).: "Myogenic differentiation potential of human tonsil-derived mesenchymal stem cells and their potential for use to promote skeletal muscle regeneration." in: International journal of molecular medicine, Vol. 37, Issue 5, pp. 1209-20, (2016) (PubMed).
: "Myostatin deficiency but not anti-myostatin blockade induces marked proteomic changes in mouse skeletal muscle." in: Proteomics, Vol. 16, Issue 14, pp. 2019-27, (2016) (PubMed).
: "Dietary L-arginine supplementation affects the skeletal longissimus muscle proteome in finishing pigs." in: PLoS ONE, Vol. 10, Issue 1, pp. e0117294, (2015) (PubMed).
: "Troponin-like regulation in muscle thin filaments of the mussel Crenomytilus grayanus (Bivalvia: Mytiloida)." in: Biochimica et biophysica acta, Vol. 1854, Issue 10 Pt A, pp. 1444-50, (2015) (PubMed).
: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).
: "Tbx20 promotes cardiomyocyte proliferation and persistence of fetal characteristics in adult mouse hearts." in: Journal of molecular and cellular cardiology, Vol. 62, pp. 203-13, (2013) (PubMed).
: "Myocardial Mycn is essential for mouse ventricular wall morphogenesis." in: Developmental biology, Vol. 373, Issue 1, pp. 53-63, (2012) (PubMed).
: "Secretome of apoptotic peripheral blood cells (APOSEC) confers cytoprotection to cardiomyocytes and inhibits tissue remodelling after acute myocardial infarction: a preclinical study." in: Basic research in cardiology, Vol. 106, Issue 6, pp. 1283-97, (2011) (PubMed).
: "Identification of a region of troponin I important in signaling cross-bridge-dependent activation of cardiac myofilaments." in: The Journal of biological chemistry, Vol. 282, Issue 1, pp. 183-93, (2007) (PubMed).
Synonyms and alternative names related to TNNI1
troponin T1, slow skeletal type (TNNT1), troponin I1, slow skeletal type (TNNI1), troponin I, skeletal, slow 1 (Tnni1), troponin I1, slow skeletal type (Tnni1), troponin T1, skeletal, slow (Tnnt1), troponin T1, slow skeletal type (Tnnt1), troponin I1, slow skeletal type S homeolog (tnni1.S), troponin I type 1 (skeletal, slow) (TNNI1), troponin I4b, tandem duplicate 2 (tnni4b.2), 2700018B22Rik, AI747285, ANM, AW146156, Fang2, NEM5, SSTNI, ssTnI, ssTnT, STNT, sTnT, TnI-S4, TNN1, TNT, Tnt, TNTS, tnTs, troponin 1, zgc:86895Protein level used designations for TNNI1
- nemaline myopathy type 5
- slow skeletal muscle troponin T
- troponin T, slow skeletal muscle
- troponin-T1, skeletal, slow
- sTnT
- tnTs
- troponin T1, skeletal, slow
- troponin T slow type isoform sTnT1
- troponin I, slow skeletal muscle
- troponin I, slow-twitch isoform
- Troponin I, slow isoform
- troponin I, skeletal, slow 1
- skeletal muscle slow-twitch TnT
- TnnI1
- Troponin I, slow skeletal muscle
- troponin I type 1 (skeletal, slow)
- troponin I, skeletal, slow
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