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TNKS2 Products

(Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2))
Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation of AXIN1 and AXIN2, 2 ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates poly-ADP-ribosylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination. Mediates poly-ADP-ribosylation of TERF1, thereby contributing to the regulation of telomere length. May also regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles (By similarity).$.

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Featured TNKS2 Categories

TNKS2 Antibodies

High quality antibodies with extensive validation data.

TNKS2 ELISA Kits

Reliable ELISA kits for a wide range of species.

TNKS2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TNKS2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7171500
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7435295
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS
Validations
  • (2)
Cat. No. ABIN651506
Quantity 400 μL
Datasheet Datasheet

Recommended TNKS2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970561
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1572822
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1160812
Quantity 96 tests
Datasheet Datasheet

Recommended TNKS2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323271
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7397051
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3096000
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TNKS2 products

Sidorova, Zavalishina, Kurchashova, Korsakova, Nazhimov, Frank, Kuimov: "Immunohistochemical detection of tankyrase 2 in human breast tumors and normal renal tissue." in: Cell and tissue research, Vol. 323, Issue 1, pp. 137-45, (2005) (PubMed).

Synonyms and alternative names related to TNKS2

tankyrase 2 (TNKS2), tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 (Tnks2), tankyrase 2 (Tnks2), tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 (TNKS2), tankyrase 2 (tnks2), tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase S homeolog (tnks.S), 5430432P15Rik, AA517131, AI662480, ARTD6, PARP-5b, PARP-5c, PARP5B, PARP5C, pART6, TANK2, Tank2, tankyrase-1, tankyrase-2, TNKL, tnks, TNKS-2, tnks.L, TNKS2, tnks2

Protein level used designations for TNKS2

  • ADP-ribosyltransferase diphtheria toxin-like 6
  • TNKS-2
  • TRF1-interacting ankyrin-related ADP-ribose polymerase 2
  • poly [ADP-ribose] polymerase 5B
  • tankyrase 2
  • tankyrase II
  • tankyrase-2
  • tankyrase-like protein
  • tankyrase-related protein
  • tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
  • tankyrase-2-like
  • LOW QUALITY PROTEIN: tankyrase-2
  • tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase L homeolog
  • tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase S homeolog
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