Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

TNK2 Products

(tyrosine Kinase, Non-Receptor, 2 (TNK2))

Categories

This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured TNK2 Categories

TNK2 Antibodies

High quality antibodies with extensive validation data.

TNK2 ELISA Kits

Reliable ELISA kits for a wide range of species.

TNK2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TNK2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB
Validations
  • (1)
  • (6)
Cat. No. ABIN3016190
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (4)
Cat. No. ABIN392082
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (4)
Cat. No. ABIN523561
Quantity 100 μL
Datasheet Datasheet

Recommended TNK2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971025
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960331
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380283
Quantity 2 x 96 tests
Datasheet Datasheet

Recommended TNK2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323267
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN7317144
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323266
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our TNK2 products

Hu, Xu, Yin, Zhang, Lu, Wu, Xue, Ho, Gao, Zhao, Zhang: "Ack promotes tissue growth via phosphorylation and suppression of the Hippo pathway component Expanded." in: Cell discovery, Vol. 2, pp. 15047, (2016) (PubMed).

Xie, Zen, Wang, He, Xie, Zhang, Li: "ACK1 promotes hepatocellular carcinoma progression via downregulating WWOX and activating AKT signaling." in: International journal of oncology, Vol. 46, Issue 5, pp. 2057-66, (2015) (PubMed).

Yokoyama, Miller: "Biochemical properties of the Cdc42-associated tyrosine kinase ACK1. Substrate specificity, authphosphorylation, and interaction with Hck." in: The Journal of biological chemistry, Vol. 278, Issue 48, pp. 47713-23, (2003) (PubMed).

Synonyms and alternative names related to TNK2

tyrosine kinase non receptor 2 (TNK2), tyrosine kinase, non-receptor, 2 (Tnk2), tyrosine kinase non receptor 2 (Tnk2), tyrosine kinase, non-receptor, 1 (tnk1), ACK, Ack, ACK-1, ACK1, ack1, ackb, AW552477, Cdgip, p21cdc42Hs, Pyk1, tnk2, tnk2b, wu:fj16g04, zgc:154019

Protein level used designations for TNK2

  • activated CDC42 kinase 1
  • activated Cdc42-associated kinase 1
  • activated p21cdc42Hs kinase
  • tyrosine kinase non-receptor protein 2
  • ACK-1
  • Cdc42 GTPase-inhibiting protein
  • P21cdc42Hs kinase
  • non-receptor protein tyrosine kinase ACK
  • activated CDC42 kinase 2
  • tyrosine kinase, non-receptor, 2
  • tyrosine kinase, non-receptor, 2b
You are here:
Support