TNK2 Products
(tyrosine Kinase, Non-Receptor, 2 (TNK2))
Categories
This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008].
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Featured TNK2 Categories
TNK2 Antibodies
High quality antibodies with extensive validation data.
TNK2 ELISA Kits
Reliable ELISA kits for a wide range of species.
TNK2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TNK2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
- (6)
Cat. No.
ABIN3016190
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (4)
Cat. No.
ABIN392082
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IP
Validations
- (4)
Cat. No.
ABIN523561
Quantity
100 μL
Datasheet
Datasheet
Recommended TNK2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6971025
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960331
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380283
Quantity
2 x 96 tests
Datasheet
Datasheet
Recommended TNK2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1323267
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
- (1)
Cat. No.
ABIN7317144
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1323266
Quantity
25 μg
Datasheet
Datasheet
Latest Publications for our TNK2 products
: "Ack promotes tissue growth via phosphorylation and suppression of the Hippo pathway component Expanded." in: Cell discovery, Vol. 2, pp. 15047, (2016) (PubMed).: "ACK1 promotes hepatocellular carcinoma progression via downregulating WWOX and activating AKT signaling." in: International journal of oncology, Vol. 46, Issue 5, pp. 2057-66, (2015) (PubMed).
: "Biochemical properties of the Cdc42-associated tyrosine kinase ACK1. Substrate specificity, authphosphorylation, and interaction with Hck." in: The Journal of biological chemistry, Vol. 278, Issue 48, pp. 47713-23, (2003) (PubMed).
Synonyms and alternative names related to TNK2
tyrosine kinase non receptor 2 (TNK2), tyrosine kinase, non-receptor, 2 (Tnk2), tyrosine kinase non receptor 2 (Tnk2), tyrosine kinase, non-receptor, 1 (tnk1), ACK, Ack, ACK-1, ACK1, ack1, ackb, AW552477, Cdgip, p21cdc42Hs, Pyk1, tnk2, tnk2b, wu:fj16g04, zgc:154019Protein level used designations for TNK2
- activated CDC42 kinase 1
- activated Cdc42-associated kinase 1
- activated p21cdc42Hs kinase
- tyrosine kinase non-receptor protein 2
- ACK-1
- Cdc42 GTPase-inhibiting protein
- P21cdc42Hs kinase
- non-receptor protein tyrosine kinase ACK
- activated CDC42 kinase 2
- tyrosine kinase, non-receptor, 2
- tyrosine kinase, non-receptor, 2b
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