TNFSF14 Products
(Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))
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The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
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Featured TNFSF14 Categories
TNFSF14 Antibodies
High quality antibodies with extensive validation data.
TNFSF14 ELISA Kits
Reliable ELISA kits for a wide range of species.
TNFSF14 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TNFSF14 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7436990
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IP, IHC (p)
Validations
- (5)
Cat. No.
ABIN7477811
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (4)
Cat. No.
ABIN740625
Quantity
100 μL
Datasheet
Datasheet
Recommended TNFSF14 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960260
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960261
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1672886
Quantity
96 tests
Datasheet
Datasheet
Recommended TNFSF14 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7275148
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7275147
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275149
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our TNFSF14 products
: "Extracorporeal Photochemotherapy Drives Monocyte-to-Dendritic Cell Maturation to Induce Anticancer Immunity." in: Cancer research, Vol. 78, Issue 14, pp. 4045-4058, (2018) (PubMed).: "A TNFRSF14-FcɛRI-mast cell pathway contributes to development of multiple features of asthma pathology in mice." in: Nature communications, Vol. 7, pp. 13696, (2016) (PubMed).
: "Licensed human natural killer cells aid dendritic cell maturation via TNFSF14/LIGHT." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 52, pp. E5688-96, (2014) (PubMed).
: "DcR3 binds to ovarian cancer via heparan sulfate proteoglycans and modulates tumor cells response to platinum with corresponding alteration in the expression of BRCA1." in: BMC cancer, Vol. 12, pp. 176, (2012) (PubMed).
: "Platelet-associated LIGHT (TNFSF14) mediates adhesion of platelets to human vascular endothelium." in: Thrombosis and haemostasis, Vol. 98, Issue 4, pp. 798-805, (2007) (PubMed).
: "4-1BBL induces TNF receptor-associated factor 1-dependent Bim modulation in human T cells and is a critical component in the costimulation-dependent rescue of functionally impaired HIV-specific CD8 T ..." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 12, pp. 8252-63, (2007) (PubMed).
: "LIGHT up-regulated on B lymphocytes and monocytes in rheumatoid arthritis mediates cellular adhesion and metalloproteinase production by synoviocytes." in: Arthritis and rheumatism, Vol. 56, Issue 4, pp. 1106-17, (2007) (PubMed).
: "Platelet-derived LIGHT induces inflammatory responses in endothelial cells and monocytes." in: Blood, Vol. 108, Issue 3, pp. 928-35, (2006) (PubMed).
: "LIGHT is constitutively expressed on T and NK cells in the human gut and can be induced by CD2-mediated signaling." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 2, pp. 646-53, (2005) (PubMed).
: "Herpesvirus entry mediator ligand (HVEM-L), a novel ligand for HVEM/TR2, stimulates proliferation of T cells and inhibits HT29 cell growth." in: The Journal of biological chemistry, Vol. 273, Issue 42, pp. 27548-56, (1998) (PubMed).
Synonyms and alternative names related to TNFSF14
TNF superfamily member 14 (TNFSF14), TNF superfamily member 14 (Tnfsf14), tumor necrosis factor (ligand) superfamily, member 14 (Tnfsf14), CD258, HVEM-L, HVEML, LIGHT, LTg, Ly113, TNFSF14, TR2Protein level used designations for TNFSF14
- tumor necrosis factor ligand superfamily, member 14
- tumor necrosis factor (ligand) superfamily, member 14
- delta transmembrane LIGHT
- herpes virus entry mediator ligand
- herpesvirus entry mediator A
- herpesvirus entry mediator ligand
- herpesvirus entry mediator-ligand
- ligand for herpesvirus entry mediator
- tumor necrosis factor ligand superfamily member 14
- tumor necrosis factor receptor-like 2
- tumor necrosis factor superfamily member LIGHT
- tumor necrosis factor superfamily member 14
- tumor necrosis factor superfamily, member 14
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