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TNFSF13 Products

(Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified\; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010].

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Featured TNFSF13 Categories

TNFSF13 Antibodies

High quality antibodies with extensive validation data.

TNFSF13 ELISA Kits

Reliable ELISA kits for a wide range of species.

TNFSF13 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TNFSF13 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (4)
Cat. No. ABIN6265449
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, FACS
Validations
  • (4)
Cat. No. ABIN7193558
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7173799
Quantity 100 μL
Datasheet Datasheet

Recommended TNFSF13 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6960252
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970939
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6974122
Quantity 96 tests
Datasheet Datasheet

Recommended TNFSF13 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7273873
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7273875
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7273872
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our TNFSF13 products

Gowhari Shabgah, Shariati-Sarabi, Tavakkol-Afshari, Ghasemi, Ghoryani, Mohammadi: "A significant decrease of BAFF, APRIL, and BAFF receptors following mesenchymal stem cell transplantation in patients with refractory rheumatoid arthritis." in: Gene, Vol. 732, pp. 144336, (2020) (PubMed).

Bat-Erdene, Quan, Chan, Lee, Matook, Lee, Rosales: "Neutrophil TLR4 and PKR are targets of breast cancer cell glycosaminoglycans and effectors of glycosaminoglycan-induced APRIL secretion." in: Oncogenesis, Vol. 7, Issue 6, pp. 45, (2018) (PubMed).

Gözmen, Karapnar, Tüfekçi, Vergin, Yüksel, Irken, Oren: "B-cell-activating factor, a proliferation inducing ligand and co-stimulatory molecules in the pathogenesis of immune thrombocytopenia in childhood." in: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, (2014) (PubMed).

Roderburg, Koch, Tacke, Nieuwenhuijsen, Bruensing, Vargas Cardenas, Kreggenwinkel, Vucur, Koppe, Jungebluth, Seikrit, Luedde, Trautwein, Luedde: "Serum concentrations of A Proliferation-Inducing Ligand (APRIL) are elevated in sepsis and predict mortality in critically ill patients." in: Journal of critical care, Vol. 28, Issue 5, pp. 882.e1-11, (2013) (PubMed).

Rodríguez-Bayona, Ramos-Amaya, López-Blanco, Campos-Caro, Brieva: "STAT-3 activation by differential cytokines is critical for human in vivo-generated plasma cell survival and Ig secretion." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 10, pp. 4996-5004, (2013) (PubMed).

Huard, Tran, Benkhoucha, Manzin-Lorenzi, Santiago-Raber: "Selective APRIL blockade delays systemic lupus erythematosus in mouse." in: PLoS ONE, Vol. 7, Issue 2, pp. e31837, (2012) (PubMed).

Xu, Joo, Clayton, Dullaers, Herve, Blankenship, De La Morena, Balderas, Picard, Casanova, Pascual, Oh, Banchereau: "Macrophages induce differentiation of plasma cells through CXCL10/IP-10." in: The Journal of experimental medicine, Vol. 209, Issue 10, pp. 1813-23, S1-2, (2012) (PubMed).

Guadagnoli, Kimberley, Phan, Cameron, Vink, Rodermond, Eldering, Kater, van Eenennaam, Medema: "Development and characterization of APRIL antagonistic monoclonal antibodies for treatment of B-cell lymphomas." in: Blood, Vol. 117, Issue 25, pp. 6856-65, (2011) (PubMed).

Chihara, Aranami, Sato, Miyazaki, Miyake, Okamoto, Ogawa, Toda, Yamamura: "Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 9, pp. 3701-6, (2011) (PubMed).

Matthes, Dunand-Sauthier, Santiago-Raber, Krause, Donze, Passweg, McKee, Huard: "Production of the plasma-cell survival factor a proliferation-inducing ligand (APRIL) peaks in myeloid precursor cells from human bone marrow." in: Blood, Vol. 118, Issue 7, pp. 1838-44, (2011) (PubMed).

Synonyms and alternative names related to TNFSF13

TNF superfamily member 13 (TNFSF13), tumor necrosis factor (ligand) superfamily, member 13 (Tnfsf13), acidic leucine-rich nuclear phosphoprotein 32 family member B (LOC494442), tumor necrosis factor (ligand) superfamily, member 13 (tnfsf13), TNF superfamily member 13 (Tnfsf13), tumor necrosis factor (ligand) superfamily, member 13 (TNFSF13), 2310026N09Rik, ANP32B, APRIL, April, april, CD256, SLAN, TALL-2, TALL2, Tall2, tnf13, TNLG7B, TRDL-1, Trdl1, ZTNF2

Protein level used designations for TNFSF13

  • TNF- and APOL-related leukocyte expressed ligand 2
  • a proliferation-inducing ligand
  • tumor necrosis factor ligand superfamily member 13
  • tumor necrosis factor-like protein ZTNF2
  • tumor necrosis factor-related death ligand-1
  • SLAN protein
  • Acidic leucine-rich nuclear phosphoprotein 32 family member B
  • TNF superfamily member 13
  • A proliferation-inducing ligand
  • tumor necrosis factor ligand superfamily member 13 isoform alpha proprotein
  • tumor necrosis factor (ligand) superfamily, member 13
  • tumor necrosis factor superfamily member 13
  • proliferation-inducing ligand
  • tumor necrosis factor ligand 7B
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