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TNFRSF4 Products

(Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008].

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Featured TNFRSF4 Categories

TNFRSF4 Antibodies

High quality antibodies with extensive validation data.

TNFRSF4 ELISA Kits

Reliable ELISA kits for a wide range of species.

TNFRSF4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TNFRSF4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application FACS, ELISA, IHC
Validations
  • (6)
Cat. No. ABIN5611187
Quantity 100 μL
Datasheet Datasheet
Reactivity Chimpanzee, Human
Application FACS, ELISA, IHC, IF, Coat, StM, ISt
Validations
  • (7)
Cat. No. ABIN6940817
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Non-Human Primate
Application FACS
Validations
  • (7)
  • (4)
Cat. No. ABIN2749174
Quantity 100 tests
Datasheet Datasheet

Recommended TNFRSF4 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970988
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960298
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1672893
Quantity 96 tests
Datasheet Datasheet

Recommended TNFRSF4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275391
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275392
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN6961095
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our TNFRSF4 products

Upadhyaya, Lahdenranta, Hurov, Battula, Dods, Haines, Kleyman, Kristensson, Kublin, Lani, Ma, Mudd, Repash, Van Rietschoten, Stephen, You, Harrison, Chen, McDonnell, Brandish, Keen: "Anticancer immunity induced by a synthetic tumor-targeted CD137 agonist." in: Journal for immunotherapy of cancer, Vol. 9, Issue 1, (2021) (PubMed).

Simons, Lim, Carter, Wagner, Wayham, Adler, Johnson: "Affinity maturation of antibodies by combinatorial codon mutagenesis versus error-prone PCR." in: mAbs, Vol. 12, Issue 1, pp. 1803646, (2020) (PubMed).

Lei, Zeng, Liu, Zhu, Wang, Wu, Jiang, Huang: "Crucial role of OX40/OX40L signaling in a murine model of asthma." in: Molecular medicine reports, Vol. 17, Issue 3, pp. 4213-4220, (2018) (PubMed).

Fromm, de Silva, Johannes, Patel, Hornblower, Schreiber: "Agonist redirected checkpoint, PD1-Fc-OX40L, for cancer immunotherapy." in: Journal for immunotherapy of cancer, Vol. 6, Issue 1, pp. 149, (2018) (PubMed).

Lin, Zhang, Dai, Li, Wang, Zhang, Chen, Lu: "Expression of interleukin-9 and its upstream stimulating factors in rats with ischemic stroke." in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, (2015) (PubMed).

Voo, Bover, Harline, Vien, Facchinetti, Arima, Kwak, Liu: "Antibodies targeting human OX40 expand effector T cells and block inducible and natural regulatory T cell function." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 7, pp. 3641-50, (2013) (PubMed).

Byun, Ma, Akçay, Pedergnana, Palendira, Myoung, Avery, Liu, Abhyankar, Lorenzo, Schmidt, Lim, Cassar, Migaud, Rozenberg, Canpolat, Aydogan, Fleckenstein, Bustamante, Picard, Gessain, Jouanguy et al.: "Inherited human OX40 deficiency underlying classic Kaposi sarcoma of childhood. ..." in: The Journal of experimental medicine, Vol. 210, Issue 9, pp. 1743-59, (2013) (PubMed).

Willett, McMonagle, Logan, Spiller, Schneider, Hosie: "Probing the interaction between feline immunodeficiency virus and CD134 by using the novel monoclonal antibody 7D6 and the CD134 (Ox40) ligand." in: Journal of virology, Vol. 81, Issue 18, pp. 9665-79, (2007) (PubMed).

Tanijiri, Shimizu, Uehira, Yokoi, Amuro, Sugimoto, Torii, Tajima, Ito, Amakawa, Fukuhara: "Hodgkin's reed-sternberg cell line (KM-H2) promotes a bidirectional differentiation of CD4+CD25+Foxp3+ T cells and CD4+ cytotoxic T lymphocytes from CD4+ naive T cells." in: Journal of leukocyte biology, Vol. 82, Issue 3, pp. 576-84, (2007) (PubMed).

Cousins, Graham, Tooze, Carter, Miller, Powrie, Macpherson, Butcher: "Eosinophilic bowel disease controlled by the BB rat-derived lymphopenia/Gimap5 gene." in: Gastroenterology, Vol. 131, Issue 5, pp. 1475-85, (2006) (PubMed).

Synonyms and alternative names related to TNFRSF4

TNF receptor superfamily member 4 (TNFRSF4), tumor necrosis factor receptor superfamily, member 4 (Tnfrsf4), TNF receptor superfamily member 4 (Tnfrsf4), ACT35, CD134, Ly-70, Ox40, OX40, TNFRSF4, Txgp1, TXGP1L

Protein level used designations for TNFRSF4

  • tumor necrosis factor receptor superfamily, member 4
  • tumor necrosis factor receptor superfamily member 4
  • OX40 antigen
  • OX40L receptor
  • tax-transcriptionally activated glycoprotein 1
  • ACT35 antigen
  • ATC35 antigen
  • CD134 antigen
  • OX40 cell surface antigen
  • OX40 homologue
  • TAX transcriptionally-activated glycoprotein 1 receptor
  • lymphoid activation antigene ACT35
  • tax-transcriptionally activated glycoprotein 1 receptor
  • MRC OX40
  • Tax-transcriptionally activated glycoprotein 1
  • tumor necrosis factor (ligand) superfamily member 4
  • tumor necrosis factor superfamily, member 4
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