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TNFRSF21 Products

(Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))

Categories

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. [provided by RefSeq, Jul 2008].

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Featured TNFRSF21 Categories

TNFRSF21 Antibodies

High quality antibodies with extensive validation data.

TNFRSF21 ELISA Kits

Reliable ELISA kits for a wide range of species.

TNFRSF21 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TNFRSF21 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7437356
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (1)
  • (2)
Cat. No. ABIN873098
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN1942955
Quantity 200 μL
Datasheet Datasheet

Recommended TNFRSF21 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN625288
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4885489
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN825002
Quantity 96 tests
Datasheet Datasheet

Recommended TNFRSF21 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274497
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274498
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293T Cells
Validations
  • (2)
Cat. No. ABIN4369893
Quantity 2 μg
Datasheet Datasheet

Latest Publications for our TNFRSF21 products

Strilic, Yang, Albarrán-Juárez, Wachsmuth, Han, Müller, Pasparakis, Offermanns: "Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis." in: Nature, Vol. 536, Issue 7615, pp. 215-8, (2016) (PubMed).

Achiron, Feldman, Gurevich: "Molecular profiling of glatiramer acetate early treatment effects in multiple sclerosis." in: Disease markers, Vol. 27, Issue 2, pp. 63-73, (2009) (PubMed).

Schmidt, Liu, Zhang, Song, Sandusky, Mintze, Benschop, Glasebrook, Yang, Na: "Enhanced B cell expansion, survival, and humoral responses by targeting death receptor 6." in: The Journal of experimental medicine, Vol. 197, Issue 1, pp. 51-62, (2003) (PubMed).

Rossi, Gaidano: "Messengers of cell death: apoptotic signaling in health and disease." in: Haematologica, Vol. 88, Issue 2, pp. 212-8, (2003) (PubMed).

Kasof, Lu, Liu, Speer, Mongan, Gomes, Lorenzi: "Tumor necrosis factor-alpha induces the expression of DR6, a member of the TNF receptor family, through activation of NF-kappaB." in: Oncogene, Vol. 20, Issue 55, pp. 7965-75, (2001) (PubMed).

Synonyms and alternative names related to TNFRSF21

TNF receptor superfamily member 21 (TNFRSF21), tumor necrosis factor receptor superfamily member 21 (tnfrsf21), TNF receptor superfamily member 21 (tnfrsf21), tumor necrosis factor receptor superfamily, member 21 (Tnfrsf21), TNF receptor superfamily member 21 (Tnfrsf21), tumor necrosis factor receptor superfamily, member 21 (tnfrsf21), AA959878, BM-018, CD358, DR6, dr6, im:6795346, MGC146356, R74815, TNFRSF21, tnfrsf21, TR7, wu:fa55e01, wu:fb02e11, wu:fc29a09, wu:fi27h08

Protein level used designations for TNFRSF21

  • tumor necrosis factor receptor superfamily, member 21
  • tumor necrosis factor receptor superfamily member 21-like
  • TNFR-related death receptor 6
  • death receptor 6
  • tumor necrosis factor receptor superfamily member 21
  • Death receptor 6
  • TNFR-related death receptor-6
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