TNFRSF1B Products
(Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))
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The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008].
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Featured TNFRSF1B Categories
TNFRSF1B Antibodies
High quality antibodies with extensive validation data.
TNFRSF1B ELISA Kits
Reliable ELISA kits for a wide range of species.
TNFRSF1B Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TNFRSF1B Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS
Validations
- (5)
Cat. No.
ABIN7193267
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS
Validations
- (4)
Cat. No.
ABIN7193268
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
- (3)
Cat. No.
ABIN6256994
Quantity
100 μL
Datasheet
Datasheet
Recommended TNFRSF1B ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960296
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970986
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962596
Quantity
96 tests
Datasheet
Datasheet
Recommended TNFRSF1B Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7275756
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7275760
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275765
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our TNFRSF1B products
: "Barrier Perturbation in Porcine Peyer's Patches by Tumor Necrosis Factor is Associated With a Dysregulation of Claudins." in: Frontiers in physiology, Vol. 13, pp. 889552, (2022) (PubMed).: "Tumor Necrosis Factor Alpha Effects on the Porcine Intestinal Epithelial Barrier Include Enhanced Expression of TNF Receptor 1." in: International journal of molecular sciences, Vol. 22, Issue 16, (2021) (PubMed).
: "EphB4/ TNFR2/ERK/MAPK signaling pathway comprises a signaling axis to mediate the positive effect of TNF-α on osteogenic differentiation." in: BMC molecular and cell biology, Vol. 21, Issue 1, pp. 29, (2020) (PubMed).
: "Lung IFNAR1hi TNFR2+ cDC2 promotes lung regulatory T cells induction and maintains lung mucosal tolerance at steady state." in: Mucosal immunology, Vol. 13, Issue 4, pp. 595-608, (2020) (PubMed).
: "Immature lung TNFR2- conventional DC 2 subpopulation activates moDCs to promote cyclic di-GMP mucosal adjuvant responses in vivo." in: Mucosal immunology, Vol. 12, Issue 1, pp. 277-289, (2019) (PubMed).
: "Potential Role of Soluble TNF-α Receptors in Diagnosis of Patients with Chronic Kidney Disease." in: Annals of clinical and laboratory science, Vol. 47, Issue 3, pp. 310-314, (2018) (PubMed).
: "TNFR2 ligation in human T regulatory cells enhances IL2-induced cell proliferation through the non-canonical NF-κB pathway." in: Scientific reports, Vol. 8, Issue 1, pp. 12079, (2018) (PubMed).
: "Endogenous TNFα orchestrates the trafficking of neutrophils into and within lymphatic vessels during acute inflammation." in: Scientific reports, Vol. 7, pp. 44189, (2017) (PubMed).
: "Novel strategies to mimic transmembrane tumor necrosis factor-dependent activation of tumor necrosis factor receptor 2." in: Scientific reports, Vol. 7, Issue 1, pp. 6607, (2017) (PubMed).
: "Memory Regulatory T cells Increase Only In Inflammatory Phase of Chronic Hepatitis B Infection and Related to Galectin-9/Tim-3 interaction." in: Scientific reports, Vol. 7, Issue 1, pp. 15280, (2017) (PubMed).
Synonyms and alternative names related to TNFRSF1B
TNF receptor superfamily member 1B (TNFRSF1B), tumor necrosis factor receptor superfamily, member 1b (Tnfrsf1b), TNF receptor superfamily member 1B (Tnfrsf1b), tumor necrosis factor receptor superfamily, member 1B (tnfrsf1b), CD120b, p75, p75TNFR, rank, TBPII, TNF-alphaR2, TNF-R-II, TNF-R2, TNF-R75, TNF-RII/TNFRSF1B, TNFalpha-R2, TNFBR, Tnfr-1, TNFR-II, TNFR1B, TNFR2, Tnfr2, TNFR80, TNFRII, TNFRSF1B, zgc:163064Protein level used designations for TNFRSF1B
- TNF-R2
- TNF-RII
- p75 TNF receptor
- p80 TNF-alpha receptor
- soluble TNFR1B variant 1
- tumor necrosis factor beta receptor
- tumor necrosis factor binding protein 2
- tumor necrosis factor receptor 2
- tumor necrosis factor receptor superfamily member 1B
- tumor necrosis factor receptor type II
- tumor necrosis factor receptor-II
- tumor necrosis factor receptor superfamily, member 1B
- TNF receptor beta chain
- TNFR-II
- p75 TNFR
- p75
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