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TNFRSF1A Products

(Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))

Categories

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease. [provided by RefSeq, Jul 2008].

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Featured TNFRSF1A Categories

TNFRSF1A Antibodies

High quality antibodies with extensive validation data.

TNFRSF1A ELISA Kits

Reliable ELISA kits for a wide range of species.

TNFRSF1A Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TNFRSF1A Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7442288
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, IF, ICC
Validations
  • (6)
Cat. No. ABIN1686656
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, IF, ICC
Validations
  • (6)
Cat. No. ABIN2482039
Quantity 100 μg
Datasheet Datasheet

Recommended TNFRSF1A ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
Cat. No. ABIN6960293
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6961962
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970981
Quantity 96 tests
Datasheet Datasheet

Recommended TNFRSF1A Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275759
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275764
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275755
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our TNFRSF1A products

Ng, Phang, Tan, Ng, Botross Henien, M Palanisamy, Ahmad, Abdul Kadir: "The Effects of Tocotrienol-Rich Vitamin E (Tocovid) on Diabetic Neuropathy: A Phase II Randomized Controlled Trial." in: Nutrients, Vol. 12, Issue 5, (2021) (PubMed).

Maier, Reichhart, Gonnermann, Kociok, Riechardt, Gundlach, Strauß, Joussen: "Effects of TNFα receptor TNF-Rp55- or TNF-Rp75- deficiency on corneal neovascularization and lymphangiogenesis in the mouse." in: PLoS ONE, Vol. 16, Issue 4, pp. e0245143, (2021) (PubMed).

Li, Gu, Yu, Yang, Zhang, Ba, Yin, Wang, Yin, Zhou, Li: "Inhibition of transmembrane TNF-α shedding by a specific antibody protects against septic shock." in: Cell death & disease, Vol. 10, Issue 8, pp. 586, (2020) (PubMed).

Polykratis, Martens, Eren, Shirasaki, Yamagishi, Yamaguchi, Uemura, Miura, Holzmann, Kollias, Armaka, van Loo, Pasparakis: "A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain." in: Nature cell biology, Vol. 21, Issue 6, pp. 731-742, (2019) (PubMed).

Tan, Tan, Phang, Ng, Ng, Ahmad, Palamisamy, Kadir: "Tocotrienol-rich vitamin E improves diabetic nephropathy and persists 6-9 months after washout: a phase IIa randomized controlled trial." in: Therapeutic advances in endocrinology and metabolism, Vol. 10, pp. 2042018819895462, (2019) (PubMed).

Szukiewicz, Pyzlak, Szewczyk, Stangret, Trojanowski, Bachanek, Braksator, Wejman: "High Glucose Level Disturbs the Resveratrol-Evoked Curtailment of CX3CL1/CX3CR1 Signaling in Human Placental Circulation." in: Mediators of inflammation, Vol. 2017, pp. 9853108, (2018) (PubMed).

Meng, Liu, Li, Wang, Jin, Wu, Shan, Christofferson, Qi, Yu, Li, Yuan: "Death-domain dimerization-mediated activation of RIPK1 controls necroptosis and RIPK1-dependent apoptosis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 9, pp. E2001-E2009, (2018) (PubMed).

Fauster, Rebsamen, Willmann, César-Razquin, Girardi, Bigenzahn, Schischlik, Scorzoni, Bruckner, Konecka, Hörmann, Heinz, Boztug, Superti-Furga: "Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking." in: Cell death and differentiation, (2018) (PubMed).

McCann, Crawford, Majkut, Holohan, Armstrong, Maxwell, Ong, LaBonte, McDade, Waugh, Longley: "Cytoplasmic FLIP(S) and nuclear FLIP(L) mediate resistance of castrate-resistant prostate cancer to apoptosis induced by IAP antagonists." in: Cell death & disease, Vol. 9, Issue 11, pp. 1081, (2018) (PubMed).

Goetzl, Schwartz, Abner, Jicha, Kapogiannis: "High complement levels in astrocyte-derived exosomes of Alzheimer disease." in: Annals of neurology, Vol. 83, Issue 3, pp. 544-552, (2018) (PubMed).

Synonyms and alternative names related to TNFRSF1A

TNF receptor superfamily member 1A (TNFRSF1A), tumor necrosis factor receptor superfamily, member 1a (Tnfrsf1a), TNF receptor superfamily member 1A S homeolog (tnfrsf1a.S), TNF receptor superfamily member 1A (tnfrsf1a), tumor necrosis factor receptor superfamily, member 1a (tnfrsf1a), tumor necrosis factor (TNF), TNF receptor superfamily member 1A (Tnfrsf1a), CD120a, cd120a, cTNF, FPF, fpf, MS5, p55, p55-R, p55-r, p60, TBP1, tbp1, TNF-alphaR1, TNF-R, tnf-r, TNF-R-I, TNF-R1, TNF-R55, TNFA, TNFalpha-R1, TNFAR, tnfar, Tnfr-2, TNFR1, Tnfr1, tnfr1, TNFR1-d2, TNFR55, tnfr55, TNFR60, tnfr60, TNFRI, TNFR I, TNFRp55, TNFRSF1A, wu:fj65b10, xtnfr1, zgc:85914

Protein level used designations for TNFRSF1A

  • TNF-R1
  • TNF-RI
  • TNFR-I
  • tumor necrosis factor binding protein 1
  • tumor necrosis factor receptor 1A isoform beta
  • tumor necrosis factor receptor superfamily member 1A
  • tumor necrosis factor receptor type 1
  • tumor necrosis factor-alpha receptor
  • TNF receptor alpha chain
  • TNF-alpha-R1
  • p60
  • tumor necrosis factor receptor 1
  • tumor necrosis factor receptor type I
  • p55 TNF receptor
  • tumor necrosis factor receptor p60
  • TNF Receptor 1 (TR1)
  • TNFR1
  • tumor necrosis factor type I
  • tumor necrosis factor receptor superfamily, member 1A
  • tumor necrosis factor receptor superfamily member 1A-like
  • TNF-a
  • TNF-alpha
  • cachectin
  • tumor necrosis factor (TNF superfamily, member 2)
  • tumor necrosis factor alpha
  • tumor necrosis factor ligand superfamily member 2
  • tumour necrosis factor
  • p55
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