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TNFRSF18 Products

(Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))

Categories

This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011].

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Featured TNFRSF18 Categories

TNFRSF18 Antibodies

High quality antibodies with extensive validation data.

TNFRSF18 ELISA Kits

Reliable ELISA kits for a wide range of species.

TNFRSF18 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TNFRSF18 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application FACS, ELISA, IHC
Validations
  • (6)
Cat. No. ABIN5684059
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF (p), IF (cc), IHC (p), IHC (fro)
Validations
  • (4)
Cat. No. ABIN738741
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, ELISA
Validations
  • (4)
Cat. No. ABIN7193235
Quantity 100 μL
Datasheet Datasheet

Recommended TNFRSF18 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960292
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN1672796
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN624986
Quantity 96 tests
Datasheet Datasheet

Recommended TNFRSF18 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (5)
Cat. No. ABIN7274786
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274787
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274785
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our TNFRSF18 products

Guiraud, Edwards, Squire, Babbs, Shah, Berg, Chen, Davies: "Identification of serum protein biomarkers for utrophin based DMD therapy." in: Scientific reports, Vol. 7, pp. 43697, (2018) (PubMed).

Rodríguez-Perea, Montoya, Olek, Chougnet, Velilla: "Statins increase the frequency of circulating CD4+ FOXP3+ regulatory T cells in healthy individuals." in: Journal of immunology research, Vol. 2015, pp. 762506, (2015) (PubMed).

Gan, Feng, Gu, Tan, Sun, Lv, Zhang: "Correlation of increased blood levels of GITR and GITRL with disease severity in patients with primary Sjögren's syndrome." in: Clinical & developmental immunology, Vol. 2013, pp. 340751, (2013) (PubMed).

Thiel, Kesselring, Pries, Puzik, Wittkopf, Wollenberg: "Expression of the T cell receptor αβ on a CD123+ BDCA2+ HLA-DR+ subpopulation in head and neck squamous cell carcinoma." in: PLoS ONE, Vol. 6, Issue 1, pp. e15997, (2011) (PubMed).

Mandapathil, Hilldorfer, Szczepanski, Czystowska, Szajnik, Ren, Lang, Jackson, Gorelik, Whiteside: "Generation and accumulation of immunosuppressive adenosine by human CD4+CD25highFOXP3+ regulatory T cells." in: The Journal of biological chemistry, Vol. 285, Issue 10, pp. 7176-86, (2010) (PubMed).

Han, ONeil-Andersen, Zurier, Lawrence: "CD4+CD25high T cell numbers are enriched in the peripheral blood of patients with rheumatoid arthritis." in: Cellular immunology, Vol. 253, Issue 1-2, pp. 92-101, (2008) (PubMed).

Lages, Suffia, Velilla, Huang, Warshaw, Hildeman, Belkaid, Chougnet: "Functional regulatory T cells accumulate in aged hosts and promote chronic infectious disease reactivation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 3, pp. 1835-48, (2008) (PubMed).

Tuyaerts, Van Meirvenne, Bonehill, Heirman, Corthals, Waldmann, Breckpot, Thielemans, Aerts: "Expression of human GITRL on myeloid dendritic cells enhances their immunostimulatory function but does not abrogate the suppressive effect of CD4+CD25+ regulatory T cells." in: Journal of leukocyte biology, Vol. 82, Issue 1, pp. 93-105, (2007) (PubMed).

Perez, Karamouzis, Skarlos, Ardavanis, Sotiriadou, Iliopoulou, Salagianni, Orphanos, Baxevanis, Rigatos, Papamichail: "CD4+CD25+ regulatory T-cell frequency in HER-2/neu (HER)-positive and HER-negative advanced-stage breast cancer patients." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 13, Issue 9, pp. 2714-21, (2007) (PubMed).

Barboza, Salmen, Goncalves, Colmenares, Peterson, Montes, Cartagirone, Gutiérrez, Berrueta: "Antigen-induced regulatory T cells in HBV chronically infected patients." in: Virology, Vol. 368, Issue 1, pp. 41-9, (2007) (PubMed).

Synonyms and alternative names related to TNFRSF18

TNF receptor superfamily member 18 (TNFRSF18), tumor necrosis factor receptor superfamily, member 18 (Tnfrsf18), TNF receptor superfamily member 18 (Tnfrsf18), AITR, CD357, GITR, Gitr, GITR-D, TNFRSF18

Protein level used designations for TNFRSF18

  • tumor necrosis factor receptor superfamily member 18
  • glucocorticoid-induced TNFR-related
  • tumor necrosis factor receptor superfamily, member 18
  • glucocorticoid-induced TNFR-related protein
  • TNF receptor superfamily activation-inducible protein
  • activation-inducible TNFR family receptor
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