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TNFRSF12A Products

(Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A))
Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.

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Featured TNFRSF12A Categories

TNFRSF12A Antibodies

High quality antibodies with extensive validation data.

TNFRSF12A ELISA Kits

Reliable ELISA kits for a wide range of species.

TNFRSF12A Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TNFRSF12A Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, FACS
Validations
  • (4)
Cat. No. ABIN7193220
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7442390
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS, IHC (fro), Func
Validations
  • (3)
  • (2)
Cat. No. ABIN2749025
Quantity 0.1 mg
Datasheet Datasheet

Recommended TNFRSF12A ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970976
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960289
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN2748712
Quantity 96 tests
Datasheet Datasheet

Recommended TNFRSF12A Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (2)
Cat. No. ABIN5509797
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275762
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN6961150
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our TNFRSF12A products

Chen, Cai, Liu: "A single molecule assay for ultrasensitive detection of Fn14 in human serum." in: Analytical biochemistry, Vol. 587, pp. 113467, (2020) (PubMed).

Connolly, Shetty, Stokum, Hoeschele, Siegel, Miller, Kim, Ho, Davila, Simard, Devine, Rossmeisl, Holland, Winkles, Woodworth: "Cross-species transcriptional analysis reveals conserved and host-specific neoplastic processes in mammalian glioma." in: Scientific reports, Vol. 8, Issue 1, pp. 1180, (2018) (PubMed).

Yoriki, Akashi, Sho, Nomi, Yamato, Hotta, Takayama, Matsumoto, Wakatsuki, Migita, Yagita, Nakajima: "Therapeutic potential of the TWEAK/Fn14 pathway in intractable gastrointestinal cancer." in: Experimental and therapeutic medicine, Vol. 2, Issue 1, pp. 103-108, (2012) (PubMed).

Huang, Narita, Tsuchiya, Ma, Numakura, Obara, Tsuruta, Saito, Inoue, Horikawa, Satoh, Habuchi: "Overexpression of Fn14 promotes androgen-independent prostate cancer progression through MMP-9 and correlates with poor treatment outcome." in: Carcinogenesis, Vol. 32, Issue 11, pp. 1589-96, (2011) (PubMed).

Roos, Wicovsky, Müller, Salzmann, Rosenthal, Kalthoff, Trauzold, Seher, Henkler, Kneitz, Wajant: "Soluble and transmembrane TNF-like weak inducer of apoptosis differentially activate the classical and noncanonical NF-kappa B pathway." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 3, pp. 1593-605, (2010) (PubMed).

Chorianopoulos, Heger, Lutz, Frank, Bea, Katus, Frey: "FGF-inducible 14-kDa protein (Fn14) is regulated via the RhoA/ROCK kinase pathway in cardiomyocytes and mediates nuclear factor-kappaB activation by TWEAK." in: Basic research in cardiology, Vol. 105, Issue 2, pp. 301-13, (2010) (PubMed).

Bover, Cardó-Vila, Kuniyasu, Sun, Rangel, Takeya, Aggarwal, Arap, Pasqualini: "A previously unrecognized protein-protein interaction between TWEAK and CD163: potential biological implications." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 12, pp. 8183-94, (2007) (PubMed).

Girgenrath, Weng, Kostek, Browning, Wang, Brown, Winkles, Michaelson, Allaire, Schneider, Scott, Hsu, Yagita, Flavell, Miller, Burkly, Zheng: "TWEAK, via its receptor Fn14, is a novel regulator of mesenchymal progenitor cells and skeletal muscle regeneration." in: The EMBO journal, Vol. 25, Issue 24, pp. 5826-39, (2006) (PubMed).

Brown, Richards, Hanscom, Feng, Winkles: "The Fn14 cytoplasmic tail binds tumour-necrosis-factor-receptor-associated factors 1, 2, 3 and 5 and mediates nuclear factor-kappaB activation." in: The Biochemical journal, Vol. 371, Issue Pt 2, pp. 395-403, (2003) (PubMed).

Nakayama, Ishidoh, Kojima, Harada, Kominami, Okumura, Yagita: "Fibroblast growth factor-inducible 14 mediates multiple pathways of TWEAK-induced cell death." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 1, pp. 341-8, (2002) (PubMed).

Synonyms and alternative names related to TNFRSF12A

TNF receptor superfamily member 12A (TNFRSF12A), tumor necrosis factor receptor superfamily, member 12a (Tnfrsf12a), TNF receptor superfamily member 12A (Tnfrsf12a), AI255180, C87282, CD266, FN14, Fn14, HPIP, TWEAK-R, TWEAKR, TweakR

Protein level used designations for TNFRSF12A

  • FGF-inducible 14
  • fibroblast growth factor-inducible immediate-early response protein 14
  • tumor necrosis factor receptor superfamily member 12A
  • tweak-receptor
  • type I transmembrane protein Fn14
  • fibroblast growth factor regulated protein 2
  • fibroblast growth factor-regulated protein 2
  • fibroblast growth factor-inducible 14
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