TNFRSF10B Products
(Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
Categories
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009].
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Featured TNFRSF10B Categories
TNFRSF10B Antibodies
High quality antibodies with extensive validation data.
TNFRSF10B ELISA Kits
Reliable ELISA kits for a wide range of species.
TNFRSF10B Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TNFRSF10B Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7442663
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (4)
Cat. No.
ABIN7271062
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (1)
- (4)
Cat. No.
ABIN5518794
Quantity
100 μg
Datasheet
Datasheet
Recommended TNFRSF10B ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970967
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960278
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960279
Quantity
96 tests
Datasheet
Datasheet
Recommended TNFRSF10B Proteins
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Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7275780
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275784
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275779
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our TNFRSF10B products
: "HIF-1α Mediates TRAIL-Induced Neuronal Apoptosis via Regulating DcR1 Expression Following Traumatic Brain Injury." in: Frontiers in cellular neuroscience, Vol. 14, pp. 192, (2020) (PubMed).: "LY3009120, a pan-Raf kinase inhibitor, inhibits adipogenesis of 3T3-L1 cells by controlling the expression and phosphorylation of C/EBP-α, PPAR-γ, STAT‑3, FAS, ACC, perilipin A, and AMPK." in: International journal of molecular medicine, Vol. 42, Issue 6, pp. 3477-3484, (2019) (PubMed).
: "Sphingomyelin synthase 2 overexpression promotes cisplatin-induced apoptosis of HepG2 cells." in: Oncology letters, Vol. 15, Issue 1, pp. 483-488, (2018) (PubMed).
: "Meridianin C inhibits the growth of YD-10B human tongue cancer cells through macropinocytosis and the down-regulation of Dickkopf-related protein-3." in: Journal of cellular and molecular medicine, Vol. 22, Issue 12, pp. 5833-5846, (2018) (PubMed).
: "High-efficiency antibody discovery achieved with multiplexed microscopy." in: Microscopy (Oxford, England), Vol. 65, Issue 4, pp. 341-52, (2018) (PubMed).
: "Targeting scFv-Fc-scTRAIL fusion proteins to tumor cells." in: Oncotarget, Vol. 9, Issue 13, pp. 11322-11335, (2018) (PubMed).
: "Dual role of DR5 in death and survival signaling leads to TRAIL resistance in cancer cells." in: Cell death & disease, Vol. 8, Issue 8, pp. e3025, (2018) (PubMed).
: "Potential Role of CD133 Expression in the Susceptibility of Human Liver Cancer Stem-Like Cells to TRAIL." in: Oncology research, Vol. 24, Issue 6, pp. 495-509, (2017) (PubMed).
: "The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2." in: Molecular cell, Vol. 65, Issue 4, pp. 730-742.e5, (2017) (PubMed).
: "TNF-Related Apoptosis-Inducing Ligand (TRAIL)-Armed Exosomes Deliver Proapoptotic Signals to Tumor Site." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 22, Issue 14, pp. 3499-512, (2016) (PubMed).
Synonyms and alternative names related to TNFRSF10B
tumor necrosis factor receptor superfamily, member 10b (Tnfrsf10b), tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), tumor necrosis factor receptor superfamily member 10b S homeolog (tnfrsf10b.S), tumor necrosis factor receptor superfamily member 10b L homeolog (tnfrsf10b.L), tumor necrosis factor receptor superfamily member 10b (tnfrsf10b), TNF receptor superfamily member 10b (TNFRSF10B), cd262, CD262, dr5, DR5, killer, KILLER, KILLER/DR5, Ly98, MK, TNFRSF10B, TRAIL-R2, trailr2, TRAILR2, trick2, TRICK2, trick2a, TRICK2A, trick2b, TRICK2B, trickb, TRICKB, xDR-M1, xDR-M2, ztnfr9, ZTNFR9Protein level used designations for TNFRSF10B
- tumor necrosis factor receptor superfamily, member 10b
- death receptor-M2
- death receptor-M1
- Fas-like protein
- TNF-related apoptosis-inducing ligand receptor 2
- apoptosis inducing protein TRICK2A/2B
- apoptosis inducing receptor TRAIL-R2
- cytotoxic TRAIL receptor-2
- death domain containing receptor for TRAIL/Apo-2L
- death receptor 5
- p53-regulated DNA damage-inducible cell death receptor(killer)
- tumor necrosis factor receptor superfamily member 10B
- tumor necrosis factor receptor-like protein ZTNFR9
- KILLER/DR5 TRAIL death-inducing receptor
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