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TNFAIP3 Products

(Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3))
This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2012].

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Featured TNFAIP3 Categories

TNFAIP3 Antibodies

High quality antibodies with extensive validation data.

TNFAIP3 ELISA Kits

Reliable ELISA kits for a wide range of species.

TNFAIP3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TNFAIP3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (1)
  • (7)
Cat. No. ABIN3022985
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
Cat. No. ABIN6265632
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7443089
Quantity 100 μL
Datasheet Datasheet

Recommended TNFAIP3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960304
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6208002
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5659643
Quantity 96 tests
Datasheet Datasheet

Recommended TNFAIP3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125559
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323130
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323128
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our TNFAIP3 products

Ma, Xiao, Tian, Chen, Zhang, Wu, Wu, Li, Tang, Yang, Zhou, Wang, Su, Wang: "Genome-wide analyses of long non-coding RNA expression profiles and functional network analysis in esophageal squamous cell carcinoma." in: Scientific reports, Vol. 9, Issue 1, pp. 9162, (2019) (PubMed).

Bao, Fan, Zhao, Xu, Liu, Chao, Liu, You, Liu, Wang, Ji: "Silencing of A20 Aggravates Neuronal Death and Inflammation After Traumatic Brain Injury: A Potential Trigger of Necroptosis." in: Frontiers in molecular neuroscience, Vol. 12, pp. 222, (2019) (PubMed).

Lim, Maubach, Sokolova, Feige, Diezko, Buchbinder, Backert, Schlüter, Lavrik, Naumann: "Pathogen-induced ubiquitin-editing enzyme A20 bifunctionally shuts off NF-κB and caspase-8-dependent apoptotic cell death." in: Cell death and differentiation, Vol. 24, Issue 9, pp. 1621-1631, (2017) (PubMed).

He, Ma, Tian, Wei, Zhu, Li, Zhang, Wang, Zhang, Zhong: "ERRα negatively regulates type I interferon induction by inhibiting TBK1-IRF3 interaction." in: PLoS pathogens, Vol. 13, Issue 6, pp. e1006347, (2017) (PubMed).

Reihill, Malcomson, Bertelsen, Cheung, Czerwiec, Barsden, Elborn, Dürkop, Hirsch, Ennis, Kelly, Schock: "Induction of the inflammatory regulator A20 by gibberellic acid in airway epithelial cells." in: British journal of pharmacology, Vol. 173, Issue 4, pp. 778-89, (2016) (PubMed).

Zong, Li, Zeng, Fang, Zhao: "The Effects of Interleukin-17 (IL-17)-Related Inflammatory Cytokines and A20 Regulatory Proteins on Astrocytes in Spinal Cord Cultured In Vitro." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 38, Issue 3, pp. 1100-10, (2016) (PubMed).

Perez, Jukica, Listopad, Anders, Kühl, Loddenkemper, Blankenstein, Charo: "Permissive expansion and homing of adoptively transferred T cells in tumor-bearing hosts." in: International journal of cancer, Vol. 137, Issue 2, pp. 359-71, (2015) (PubMed).

De, Dainichi, Rathinam, Ghosh: "The deubiquitinase activity of A20 is dispensable for NF-κB signaling." in: EMBO reports, Vol. 15, Issue 7, pp. 775-83, (2014) (PubMed).

de Jong, Verhaar, Chen, Vader, Gremmels, Posthuma, Schiffelers, Gucek, van Balkom: "Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes." in: Journal of extracellular vesicles, Vol. 1, (2013) (PubMed).

Lai, Wu, Tsai, Chuang, Chuang, Hsu, Lai: "Transcription of Tnfaip3 is regulated by NF-κB and p38 via C/EBPβ in activated macrophages." in: PLoS ONE, Vol. 8, Issue 9, pp. e73153, (2013) (PubMed).

Synonyms and alternative names related to TNFAIP3

TNF alpha induced protein 3 (TNFAIP3), TNF alpha induced protein 3 S homeolog (tnfaip3.S), tumor necrosis factor, alpha-induced protein 3 (Tnfaip3), TNF alpha induced protein 3 (Tnfaip3), A20, MGC82339, OTUD7C, TNFA1P2, tnfaip3, TNFAIP3, Tnfip3

Protein level used designations for TNFAIP3

  • tumor necrosis factor, alpha-induced protein 3
  • OTU domain-containing protein 7C
  • TNF alpha-induced protein 3
  • putative DNA-binding protein A20
  • tumor necrosis factor alpha-induced protein 3
  • tumor necrosis factor inducible protein A20
  • zinc finger protein A20
  • tumor necrosis factor induced protein 3
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