TN13B Protein (AA 68-285, Extracellular) (His-SUMO Tag)
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- Target
- TN13B (Tumor Necrosis Factor Ligand Superfamily Member 13B (TN13B))
- Protein Type
- Recombinant
- Protein Characteristics
- Extracellular, AA 68-285
- Origin
- Human
- Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TN13B protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- QVAALQGDLA SLRAELQGHH AEKLPAGAGA PKAGLEEAPA VTAGLKIFEP PAPGEGNSSQ NSRNKRAVQG PEETVTQDCL QLIADSETPT IQKGSYTFVP WLLSFKRGSA LEEKENKILV KETGYFFIYG QVLYTDKTYA MGHLIQRKKV HVFGDELSLV TLFRCIQNMP ETLPNNSCYS AGIAKLEEGD ELQLAIPREN AQISLDGDVT FFGALKLL
- Purification
- SDS-PAGE
- Purity
- > 90 %
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
-
- Target
- TN13B (Tumor Necrosis Factor Ligand Superfamily Member 13B (TN13B))
- Alternative Name
- TN13B
- Background
- Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response.
- Molecular Weight
- 39.7 kDa
- UniProt
- Q9Y275
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